A, S., A, E., Madkour, N., A, E., Ebied, E., Saleh, N., Kalad, M. (2011). Preparation of Combined Equine Influenza and Tetanus Toxoid Vaccine from local stains. test, 59(3), 423-433. doi: 10.21608/vmjg.2011.368304
Soliman A; El-Meneisy A; Nashwa Madkour; El-Helw A; Eman Ebied; Nehal Saleh; Magda Kalad. "Preparation of Combined Equine Influenza and Tetanus Toxoid Vaccine from local stains". test, 59, 3, 2011, 423-433. doi: 10.21608/vmjg.2011.368304
A, S., A, E., Madkour, N., A, E., Ebied, E., Saleh, N., Kalad, M. (2011). 'Preparation of Combined Equine Influenza and Tetanus Toxoid Vaccine from local stains', test, 59(3), pp. 423-433. doi: 10.21608/vmjg.2011.368304
A, S., A, E., Madkour, N., A, E., Ebied, E., Saleh, N., Kalad, M. Preparation of Combined Equine Influenza and Tetanus Toxoid Vaccine from local stains. test, 2011; 59(3): 423-433. doi: 10.21608/vmjg.2011.368304

Preparation of Combined Equine Influenza and Tetanus Toxoid Vaccine from local stains

Veterinary Medical Journal (Giza)
Volume 59, Issue 3, July 2011, Pages 423-433    PDF (1.74 M)
Document Type: Original Article
DOI: 10.21608/vmjg.2011.368304
Authors
Soliman A* ; El-Meneisy A; Nashwa Madkour; El-Helw A; Eman Ebied; Nehal Saleh; Magda Kalad
Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo
Abstract
   Inactivated equine influenza from local isolate and tetanus toxoid (EITT) vaccine adjuvanted with saponin was prepared. It was inoculated into Guinea pigs as a preliminary evaluation for its potency, which exceeds the permissible protective level allowed to be used for vaccination of horses. The vaccine proved to be safe and potent for horses and Guinea pigs. The mean haemagglutination inhibition (HI) antibody titres (3 weeks post vaccination) were 704 and 200 and the mean toxin neutralizing (TN) antibodies (2 weeks after boostering) were 37.9 and 45 IU/ml respectively. The antibody titre in vaccinated hones was monitored up to 6 months post re- vaccination. The keeping quality of the prepared vaccine was studied for one year. It was found to be stable when stored at 4°C.
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