IMMUNOMODULATION OF NIGELLA SATIVA AND NUTRILAC ON EXPERIMENTALLY IMMUNOSUPPRESED CHICKS BY REO-VIRUS INFECTION | ||
| Veterinary Medical Journal (Giza) | ||
| Volume 50, Issue 1, January 2002, Pages 5-15 PDF (2.99 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/vmjg.2002.369205 | ||
| Authors | ||
| S TAMAM* 1; AZZA EL-SAWAH2 | ||
| 1Dept. of Virology, Fac. Vet. Med., Beni Suef, Cairo University. | ||
| 2Dept. of Poultry Diseases, Fac. Vet. Med., Beni Suef, Cairo University. | ||
| Abstract | ||
| This work was designed to study the experimen- tally immunosuppressive effect of Reovirus infec- tion and the immunomodulating effect of either Nigella sativa seed or the acidifier nutrilac on the immune system of one- day old chicks against NewCastle disease virus inactivated vaccine and the results was measured by HIGM titer where it showed that Reovirus infection is functionally al- literate the immune system of one-day old chicks by immunosuppresion giving HIGM titer 2 com- paring with the control (non infected chicks) which gave HIGM titer 4.8 at 21 days post vacci- nation with inactivated NewCastle disease virus vaccine. On the other hands both nigella sativa and acidifiers nutrilac were a potent immunostim- mulant and can counter the immunosuppresion ef- fect induced by Reovirus infection. But Nigella Sativa seed was superior in its immunostimulant activity than the acidifier nutrilac where it gave HIGM titer 8.6 comparing with acidifier nutrilac which gave 7.4 at 21 days post vaccination with inactivated Newcastle disease virus vaccine. | ||
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