TOXOPLASMA INFECTION AMONG GOATS WITH SPECIAL REFERENCE TO ITS EFFECT ON LIVER AND KIDNEY FUNCTION | ||
| Veterinary Medical Journal (Giza) | ||
| Volume 50, Issue 3, July 2002, Pages 357-375 PDF (4.98 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/vmjg.2002.369259 | ||
| Authors | ||
| B FAHMY* 1; MARY AYOUIB2 | ||
| 1Department of Chemistry, Nutritional Deficiency Diseases and Toxicology | ||
| 2Department of Parasitology, Animal Health Institute, Dokki. | ||
| Abstract | ||
| 96 (ninety-six) goats housed in farm-Al-Amiria- Alexandria govenerate, were investigated for Toxoplasma gondii (T. gondii). Serum samples were analyzed for serological and biochemical studies to detect the liver and kidney alterations. The distribution of titer of Indirect heamagglutination Test (IHAT), Indirect Fluorescent antibody Test (IFAT) and Enzyme linked imunoassay (ELISA) was determined. The percentage of samples as test sensitive for each of these tests were 18.751, 28.12% and 31.25% for IHAT, IFAT and ELISA respectively. 66 goats (68.75%) were negative by ELISA test and 30(31.25%) was seroRase (AST) and alkaline phosphatase (ALP), and lower significant increase of urea with low significant decrease of serum total protein and alanine aminotransferase (ALT). The moderate titer of T. gondii characterized by an highly significant in- crease of serum total bilirubin, ALP and uric acid and moderate significant increase of AST, and urea and significant decrease of serum total protein and ALT. It were also detected high significant decrease of total protein with significant elevation of serum bilirubin, AST, ALP, urea was accompanied with high Toxoplasma titer. Changes in the protein profile especially albumin and B- globulin were observed. Positive. The positive were classified into low, The conclusion of this study revealed that ELISA medium and high titer on the basis of severity of infection and titer reaction. The results indicated that lower titer of Toxoplas ma antibody demonstrated highly significant in- crease of serum bilirubin, aspartate aminotransfe Is the most sensitive serological tool. Liver and kidney function are altered by T. gondii, the func tions greatly impaired especially with the pres- ence of heavy infection which appears as a high antibody titer. | ||
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