ORIC AND IMMUNOLOGIC EFFECTS OF FUMONISIN B1 ON QUAIL ND THE PROTECTIVE ROLE OF LACTOBACILLUS ACIDOPHILUS | ||
| Veterinary Medical Journal (Giza) | ||
| Volume 50, Issue 4, October 2002, Pages 807-820 PDF (3.7 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/vmjg.2002.369357 | ||
| Authors | ||
| IMAN ELSAIEED* ; M ELHADY; NAGWA RABIE | ||
| Department of Toxicology and Forensic Medicine, Faculty of Veterinary Medicine, Cairo University. Department of Parasitology and Animal Diseases, National Research Center, Dokki | ||
| Abstract | ||
| To investigate the toxic and immunologic effects of fumonisin B, (FB,) on quail and to test wheth- er Lactobacillus acidophilus (LBA) could reduce its effects, this study was performed. Quail were divided into four groups. The first, second, and third groups were fed on diets contained 25 ppm FB, or 25 ppm FB1+ 50 ppm LBA or 50 ppm LBA respectively, the fourth group served as a control. This treatment was started from the 2nd to the 6th week of age. Toxic effects of FB, were evident by the decrease of body weight gain, food consumption and food conversion and by the histopathological lesions of the intestine, liver, and kidney. Humoral and cell mediated immune responses were also affected. There were significant changes in the haemagglutination inhibition titer, electrophoretic pattern of serum protein, total and Differential leukocytic counts and the relative weights of spleen and bursa. Microscopic examination of both spleen and bursa showed pathological alterations. In the meanwhile LBA not only significantly reduced the toxic and immunosuppressive effects of FB, but also improved the nutritional and immune status of the normal birds. | ||
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