IMMUNOSUPPRESSIVE ROLE OF FLORFENICOL IN BUFFALO CALVES | ||
| Veterinary Medical Journal (Giza) | ||
| Volume 51, Issue 1, January 2003, Pages 41-47 PDF (1.63 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/vmjg.2003.375130 | ||
| Authors | ||
| H HASAAN* 1; M NASSER2 | ||
| 1Animal Reproduction Research Institute, P.o. 12556 El-haram, Giza, Egypt. | ||
| 2Dept. of Medicine; Fac. Of Vet. Med.; Kafr El-Sheikh, Tanta Univ. | ||
| Abstract | ||
| A study was designed to investigate the effect of Florfenicol therapeutic dose, 20 mg/kg body Weight intramuscularly; 2 injections 48 hours apart, on the immune competence of Egyptian Female buffalo calves (3-6 months) vaccinated with brucella abortus strain 19. Florfenicol administration elucidated a significant decline in Lymphocyte blastogenesis, chemotaxis and phagocytic activity. Throughout the estimation of antibody titre, the results disclosed Remarkable decrease of antibody levels by standard tube agglutination (SAT) and rivanol tests. It was concluded that the drug significantly suppress both cellular and humoral immune performance in Egyptian buffalo calves. | ||
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