Antimicrobial activity of marine derived fungi isolated from soft corals | ||
| Benha Journal of Applied Sciences | ||
| Article 29, Volume 9, Issue 3, March 2024, Pages 245-250 PDF (348.21 K) | ||
| Document Type: Original Research Papers | ||
| DOI: 10.21608/bjas.2024.305410.1458 | ||
| Author | ||
| Mayar M. Nassar* | ||
| Botany and Microbiology department, Faculty of Science, Benha University, Benha, Egypt. | ||
| Abstract | ||
| Marine environment is immensely complex and home to a wide variety of life forms. The water column of the ocean contains around 106 microorganisms per milliliter. Physiologically active chemicals found in marine bacteria and fungi are unusual and numerous, which makes them highly interesting. Over the past few decades, there has been a gradual increase in the amount of secondary metabolites from marine bacteria and fungi that have been reported. Drug-resistant bacterial infections, especially those involving several drug-resistant strains, have become more common due to overuse of antibiotics, and an increasing proportion of drug-unresponsive infectious disease agents is a serious threat to the world's healthcare system. From Red Sea water samples in the form of water, soil, swabs and small pieces from the studied three soft corals were collected. The fungal isolates were isolated from these four different types of samples. Antagonistic activity test was applied between fungal isolates against the two pathogenic bacteria (Pseudomonas aeruginosa ATCC-9027, Staphylococcus aureus ATCC-6538) and the diameter of inhibition zone determined. The crude extract of four chosen fungal isolates has been obtained by cultivation of the fungi on PDB broth medium for 15 days. The crude extract was tested for antibacterial activity against pathogenic bacteria. our study revealed various marine fungi from different soft corals species, the foremost report of different Aspergillus sp. The result demonstrate that these marine fungi serve as potent producers of antibacterial secondary metabolites. It also evident that they can serve as potential antibacterial mediators against pathogenic bacteria. | ||
| Keywords | ||
| Soft corals; Marine fungi; Secondary metabolites; Antibacterial activity | ||
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