DIMITRI, R., MIKHAIL, D., AMIN, M., GERGIS, S., SHAWKAT, H., AWAD, W. (1991). DELAYED HYPERSENSITIVITY AND HUMORAL IMMUNE RESPONSE IN STEERS EXPERIMENTALLY INFECTED WITH DIFFERENT STRAINS OF MYCOBACTERIA. test, 39(1), 29-45. doi: 10.21608/vmjg.1991.379035
R.A. DIMITRI; D.G. MIKHAIL; M.M. AMIN; S.N. GERGIS; H.E. SHAWKAT; W.H. AWAD. "DELAYED HYPERSENSITIVITY AND HUMORAL IMMUNE RESPONSE IN STEERS EXPERIMENTALLY INFECTED WITH DIFFERENT STRAINS OF MYCOBACTERIA". test, 39, 1, 1991, 29-45. doi: 10.21608/vmjg.1991.379035
DIMITRI, R., MIKHAIL, D., AMIN, M., GERGIS, S., SHAWKAT, H., AWAD, W. (1991). 'DELAYED HYPERSENSITIVITY AND HUMORAL IMMUNE RESPONSE IN STEERS EXPERIMENTALLY INFECTED WITH DIFFERENT STRAINS OF MYCOBACTERIA', test, 39(1), pp. 29-45. doi: 10.21608/vmjg.1991.379035
DIMITRI, R., MIKHAIL, D., AMIN, M., GERGIS, S., SHAWKAT, H., AWAD, W. DELAYED HYPERSENSITIVITY AND HUMORAL IMMUNE RESPONSE IN STEERS EXPERIMENTALLY INFECTED WITH DIFFERENT STRAINS OF MYCOBACTERIA. test, 1991; 39(1): 29-45. doi: 10.21608/vmjg.1991.379035

DELAYED HYPERSENSITIVITY AND HUMORAL IMMUNE RESPONSE IN STEERS EXPERIMENTALLY INFECTED WITH DIFFERENT STRAINS OF MYCOBACTERIA

Veterinary Medical Journal (Giza)
Volume 39, Issue 1, January 1991, Pages 29-45    PDF (8.62 M)
DOI: 10.21608/vmjg.1991.379035
Authors
R.A. DIMITRI* 1; D.G. MIKHAIL1; M.M. AMIN2; S.N. GERGIS1; H.E. SHAWKAT2; W.H. AWAD1
1Vet. Serum and Vaccine Research Institute
2Faculty of Vet. Med. Cairo University
Abstract
Animals infected with mycobacteria are allergic to the protein contained in PPD tuberculin and develop characteristic delayed type hypersensitivity react- ions when exposed to tuberculoproteins in tuberculin. If tuberculin is deposited in the skin (intradermally), a local reaction characterized by inflammation and swelling usually is elicited in infected animals, whereas healthy animals fail to develop such responses at the injection site (Thoen, 1988). The comparative tuberculin test in which two or more tuberculins are injected simultaneously offers advantages in differentiating infection with M. bovis from various non-specific infections (Francis et al., 1978). The tuberculin positive cattle show also changes in the serum protein constituents (Moses et al., 1975 and Gatner et al., 1982). The aim of this study was to follow up the delayed hypersensitivity responses in steers infected with a variety of mycobacterial species and the changes in the immune response determined by immunoglobulin levels in their sera.
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