El Badawi, N., Yassin, H., Farag, A., Abdalwahab, M., Gamal, A. (2024). Periodontally Involved Root Surfaces Biocompatibility following Application of Different Curcumin Concentration (In Vitro Study). test, 10(3), 600-607. doi: 10.21608/jbaar.2024.381634
Noorhan K. El Badawi; Hala H. Yassin; Amina F Farag; Mahetab M. Abdalwahab; Ahmed Y Gamal. "Periodontally Involved Root Surfaces Biocompatibility following Application of Different Curcumin Concentration (In Vitro Study)". test, 10, 3, 2024, 600-607. doi: 10.21608/jbaar.2024.381634
El Badawi, N., Yassin, H., Farag, A., Abdalwahab, M., Gamal, A. (2024). 'Periodontally Involved Root Surfaces Biocompatibility following Application of Different Curcumin Concentration (In Vitro Study)', test, 10(3), pp. 600-607. doi: 10.21608/jbaar.2024.381634
El Badawi, N., Yassin, H., Farag, A., Abdalwahab, M., Gamal, A. Periodontally Involved Root Surfaces Biocompatibility following Application of Different Curcumin Concentration (In Vitro Study). test, 2024; 10(3): 600-607. doi: 10.21608/jbaar.2024.381634

Periodontally Involved Root Surfaces Biocompatibility following Application of Different Curcumin Concentration (In Vitro Study)

Journal of Bioscience and Applied Research
Volume 10, Issue 3, September 2024, Pages 600-607    PDF (784.56 K)
Document Type: Original Article
DOI: 10.21608/jbaar.2024.381634
Authors
Noorhan K. El Badawi* 1; Hala H. Yassin2; Amina F Farag3; Mahetab M. Abdalwahab4; Ahmed Y Gamal5
1Department of Periodontology, Faculty of Dentistry, October 6 University.
2Department of Oral Medicine, Periodontology, Oral Diagnosis and Oral Radiology, College of Dentistry at Arab Academy for Science and Technology and Maritime Transport AASTMT, New Alamein Alexandria, Egypt
3Department of Oral and Maxillofacial Pathology Department Attachment Faculty of Dentistry, October 6 University, Egypt
4Department of Oral Medicine, Periodontology, Oral Diagnosis and Oral Radiology, Faculty of Dentistry, Russian University, Cairo, Egypt.
5Department of Periodontology, Faculty of Dentistry. Ain Shams University and Misr University for Science and Technology, Egypt
Abstract
This study aimed to assess the impact of 0.12%, 1%, and 2% curcumin concentrations on the adherence of periodontal ligament cells to root surfaces damaged by periodontal disease. Materials and Methods: Twenty periodontally compromised teeth were removed and sectioned into root specimens. PDL fibroblasts were harvested from freshly extracted teeth for orthodontic purposes, and subsequently grown and incubated. PDL fibroblast cells were then introduced to curcumin-coated root samples at varying dosages. The study samples were categorized into four groups: Group 1 (0.12% curcumin paste), Group 2 (1% curcumin paste), Group 3 (2% curcumin paste), and Group 4 (control group). All samples were examined using a scanning electron microscope. Results: Group 3, with a 2% curcumin concentration, exhibited distinctly defined multilayered adhering cells that encompassed the whole surface, characterized by entirely flat polyhedral bodies featuring elongated cytoplasmic extensions and minimal to no bacterial colonization, along with sporadic isolated planktonic bacterial adherence.
Conclusion: Curcumin at 2% concentration optimally stimulates cellular attachment and exhibits antibacterial properties on root surfaces damaged by periodontitis.
Keywords
Periodontal ligament fibroblast; curcumin concentration; root surface
Statistics
Article View: 123
PDF Download: 143