تأثير الكركمين علي جرثومة المعدة في فئران التجارب Effect of Curcumin on Helicobacter pylori in Experimental Rats | ||
| حوار جنوب جنوب | ||
| Volume 7, Issue 23, October 2024, Pages 99-118 PDF (956.08 K) | ||
| Document Type: المقالة الأصلية | ||
| DOI: 10.21608/hgg.2024.324088.1128 | ||
| Authors | ||
| أسماء محمد فتحي عبدالمحسن* 1; سعاد محمد عمر2; هند محمد علي3; محمود عشري إبراهيم عبد التواب4 | ||
| 1كلية التربية النوعية جامعة أسيوط | ||
| 2استاذ التغذية وعلوم الاطعمة المتفرغ _قسم اقتصاد منزلي-كلية التربية النوعية-جامعة اسيوط | ||
| 3أستاذ التغذية وعلوم الاطعمه _رئيس قسم الاقتصاد المنزلي_كلية التربية النوعية_جامعة اسيوط | ||
| 4كلية العلوم - جامعة الأزهر فرع أسيوط | ||
| Abstract | ||
| Helicobacter pylori (H. pylori) is a spiral shaped bacterium that lives and multiplies in the lining of the stomach, and it is a common cause of many stomach diseases. This study aims to show the effect of curcumin on helicobacter pylori in experimental rats .Sixty adult male albino rats,were randomly into six groups (10 rats each). as follows: Group (1): composed of normal rats as negative control groups(-ve), Group (2): composed of rats those were subjected to oral administration of at a dose (200 mg/kg/day) CAE. Group (3): composed of rats those were subjected to oral administration of at a dose (400 mg/kg/day) CAE.Group (4): composed of rats those were subjected to injection of (1mL/rat) twice daily) H. pylori act as a positive control(+ve).Group (5): comprise of rats infected by H. pylori those were treated oral with at a dose (200 mg/kg/day) CAE and Group (6): comprise of rats infected by H. pylori those were treated oral with at a dose (400 mg/kg/day) CAE, for six weeks . The results revealed that curcuma aqueous extract had 15 Phenolic constituents . Besides results indicated that the rats treated with CAE 200 and 400 mg/kg/day showed significantly decreased in serum cholesterol, triglycerides, glucose and LDL-C matched with a significant increase in serum HDL-C, In addition , at (p≤0.05) there were decreased ,serum ALT, AST, ALP, and GGT, Also, serum urea, creatinine, and uric acid levels, when compared with group (4), So this study recommended using curcumin in diets for its many benefits. | ||
| Keywords | ||
| Helicobacter pylori (H. pylori)؛ curcumin؛ Antioxidant؛ Lipids profile and Liver and Kidney Function جرثومة المعدة; الكركمين; مضادات الاكسدة; دهون الدم; وظائف الكبد والكلي | ||
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