Evaluation of the Immunological Response of Local and Imported Vaccines of Lumpy Skin Disease Virus in Cattle as Preventive Step | ||
| Egyptian Journal of Veterinary Sciences | ||
| Articles in Press, Corrected Proof, Available Online from 13 October 2024 PDF (1.04 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejvs.2024.306220.2272 | ||
| Authors | ||
| sara fayez Awad* 1; Shaaban saber khalafallah2; Gamil SG Zeedan3; Aya Elsayed Azam4; Halla Kasem El Bahgy4 | ||
| 1Veterinary hygiene and management,faculty of veterinary medicine | ||
| 2Animal, Poultry and Environmental Hygiene, Department of Veterinary Hygiene and Management, Faculty of Veterinary Medicine, Benha University, Benha 13736, Egypt. | ||
| 3National Research Centre | ||
| 4Department of Veterinary Hygiene and Management, Faculty of Veterinary Medicine, Benha University, Benha 13736, Egypt. | ||
| Abstract | ||
| Vaccination process against lumpy skin disease (LSD) is considered the only effective method for the prevention and control of LSD in endemic areas, where neutralizing antibodies play an important role in long-term protection after vaccination. A total of 260 sera samples were collected from 20 bulls, their ages ranged from 9 to 12 months. These bulls were divided into groups (each group containing 10 bulls) in beef farms at Monsha,t El kanater Aboghaleb, Giza Governorate, Egypt. This study was carried out from November 2022 to May 2023. One of these groups was vaccinated with the local strain (SERVAC CAPRI-C®) and the other was immunised with the imported strain (BOVIVAX LSD®). The serum sampling was carried out before vaccination and till 6 months with intervals 2 weeks after vaccination. Our study aimed to determine the efficacy of both vaccines in cattle immunity for evaluating vaccinated cattle's humeral immune response against the Neethling strain vaccine. Our results revealed that the titer of antibodies against BOVIVAX LSD® appeared to highly significantly increase (P>0.05) throughout the experiment when compared with (SERVAC CAPRI-C®) which showed a slight numerical increase and then significantly decreased at 24 weeks post-vaccination. Likewise, the vaccination process might slightly affect some parameters of liver dysfunctions mainly the alanine transaminase test. In conclusion, live attenuated BOVIVAX LSD® vaccine has a great ability to induce a high level of antibody titer with prolongation of immunity duration, so it is considered the best choice of vaccine for prevention and control of LSD that can applied in the field. | ||
| Keywords | ||
| Lumpy skin disease; Neethling strain; Vaccine; Immunity; Prevention | ||
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