Enterobacter cloacae Complex: An emerging pathogen with increasing rates of antibiotic resistance in a Tunisian Hospital | ||
| Microbes and Infectious Diseases | ||
| Articles in Press, Accepted Manuscript, Available Online from 15 October 2024 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mid.2024.323434.2243 | ||
| Authors | ||
| Syrine Chemli; Yosr Kadri; Ons Haddad; Yassmine Maatouk* ; Maha Mastouri | ||
| Microbiology Laboratory, Fattouma Bourguiba University Hospital, Monastir, Tunisia | ||
| Abstract | ||
| Background: Enterobacter cloacae is an opportunistic pathogen responsible for various diseases that may be difficult to handle due to the emergence of resistant strains. Our study aimed to describe the epidemiological profile of E. cloacae isolates and to establish an inventory of their antibiotic resistance patterns. Methods: A retrospective study, conducted at the Microbiology Laboratory in the Fattouma Bourguiba University Hospital, in Monastir, over a decade. All strains of E. cloacae gathered during the study period were included. Bacterial identification was performed by conventional methods. Antibiotic susceptibility study was based on the CA-SFM/EUCAST. Results: A total of, 1343 strains of E. cloacae were collected mainly from the adult population. Strains were mainly gathered from surgical departments. Most samples were skin and soft tissue infections. Over a quarter of the strains were considered multidrug-resistant bacteria showing resistance to cephalosporines at 26.2% and to carbapenems at 6.2% of the strains. Carbapenemase-producing strains originated mainly from the General Surgery Department and Surgical Intensive Care Unit Department in 30% and 21% respectively. Conclusion: The prevalence of E. cloacae is increasing. The emergence of resistance to cephalosporins and carbapenems seems alarming, requiring more effort to limit its emergence. | ||
| Keywords | ||
| Enterobacter cloacae; antimicrobial resistance; multidrug-resistant | ||
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