Harmal nanoparticles as potential anti obese, promises for natural control of obesity | ||
| Bulletin of Faculty of Science, Zagazig University | ||
| Article 1, Volume 2024, Issue 3, October 2024, Pages 1-5 PDF (657.32 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bfszu.2024.239359.1318 | ||
| Author | ||
| Mervat Abdelsattar Farg* | ||
| Faculty of science, Zagazig | ||
| Abstract | ||
| The current investigation looked at how changes in serum glucose and liver enzymes in rats given a high-calorie diet (HCD) to make them fat were affected by a methanolic extract of P. harmala/ nanopartical (H/ZnONP) extract. Half of the rats became obese after being given HCD for a month. The 36 male rats were split into two groups (normal and obese), each of which had three subgroups.For a month, the main group received H/ZnONP 200 and 400 mg/kg BW/day orally, while the control group of people continued to be overweight and normal. Blood was drawn and tested at a lab for glucose levels and liver enzymes after 4 weeks of treatment. The collected results showed that giving obese rats H/ZnONP considerably reduced serum glucose levels as well as ALT and AST enzymes. According to the data, supplementing rats with H/ZnONP has a powerful anti-obesity effect via elevating glucose levels, especially at high doses. From the data, we may infer that high-dose H/ZnONP supplementation has effective anti-obesity effects in rats through enhancing glucose levels and liver function. Keywords: Obesity; Methanolic extract of P. harmala / ZnO nanoparticles | ||
| Keywords | ||
| Harmal; obesity; zinc oxide nanoparticles | ||
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