التأثير المحسن لبذور الريحان ضد الإجهاد التأكسدي الناجم عن أحادي جلوتامات الصوديوم في الفئران | ||
| المجلة العلمية للتربية النوعية والعلوم التطبيقية | ||
| Volume 7, Issue 22, October 2024, Pages 126-156 PDF (558.26 K) | ||
| Document Type: المقالة الأصلية | ||
| DOI: 10.21608/sjseas.2024.321643.1014 | ||
| Authors | ||
| لمياء عبد الحميد دياب* 1; ,وفاء أحمد رفعت2 | ||
| 1قسم التغذية وعلوم الأطعمة – كلية الاقتصاد المنزلى – جامعة المنوفية, شبين الكوم, مصر | ||
| 2قسم التغذية وعلوم الأطعمة – كلية الاقتصاد المنزلى – جامعة المنوفية,شبين الكوم مصر. | ||
| Abstract | ||
| This study was conducted to evaluate the modulatory effect of basil seed powder (BSP) on MSG-induced oxidative stress in rats. In this regard, thirty rats weighing 150 ± 10.86 g were used for the study and separated into 5 groups . Group 1(-): control negative group; group 2(+): MSG only as control positive group; groups 3, 4, and 5 were given MSG and treated with (2.5, 5, and 7.5 g/100 g diet) BSP, respectively. The MSG groups were given a 4 mg/kg b.wt. daily oral dose of MSG. After completing 28 days, the biological parameters were ameliorated by BSP intervention (2.5, 5, and 7.5 g/100 g diet). The use of BSP reversed the negative effects of MSG on liver oxidative stress parameters. The BSP-treated (7.5 g/100 g diet) group recorded an improvement, reaching the point of no significant difference with the negative group in SOD. In addition, our results revealed that the MSG-treated group shows a significant change in deterioration in hematological parameters, liver enzymes, some kidney function, serum glucose, and lipid profile. Interestingly, BSP (2.5, 5, and 7.5 g/100 g diet) administration demonstrated the ability to significantly (p≤0.05) alleviate these toxic effects dose-dependently. Histological observations of liver tissue provided evidence for the ameliorative effect of BSP. The study noted the harmful effects of MSG and suggested BSP as a potential remedy for MSG oxidative stress | ||
| Keywords | ||
| بذور الريحان; الشوارد الحرة; محسن النكهة; حمض اللينولينك | ||
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