Prediabetes and Diabetes in Overweight and Obese Egyptian Men | ||
| Journal of Recent Advances in Medicine | ||
| Articles in Press, Accepted Manuscript, Available Online from 19 November 2024 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jram.2024.320351.1265 | ||
| Authors | ||
| Sherif Sabry Ayoub* 1; Fatma Kamel Hammad2; Marwa Fekry Mohamed Elsayed3 | ||
| 1Independent Doctor, Department of Endocrinology, Cairo Egypt | ||
| 2Professor of Endocrinology, Faculty of medicine for girls Cairo Al Azhar University | ||
| 3Lecturer of Endocrinology, Faculty of medicine for girls Cairo Al Azhar university | ||
| Abstract | ||
| Background: Diabetes mellitus (DM) is a significant public health issue that is characterized by impaired carbohydrate metabolism, lipid, and protein as a result of insulin resistance, inadequate insulin secretion, or both. We aimed to indicate the pre-diabetes and type 2 DM prevalence in overweight and obese adult population as well as the relation of blood sugar parameters to the obesity indices in overweight and obese males. Methods: This cross-sectional comparative study was performed on 211 attendance apparently healthy adult males attending the primary care clinic of Beverages and Snacks plants in Egypt aged from 30-60 years with no history of diabetes for the last 6 months ending in September 2023. Patients were categorized into three groups regarding body mass index (BMI): Group A (Normal weight (BMI < 25 Kg/m2) 35 cases). Group B (Overweight (BMI between 25-29.9 kg/m2) 95 cases), Group C (Obese (BMI ≥ 30 Kg/m2) 81 cases). Results: Six (17%) patients from group A were pre-diabetic, while 29 (30.5%) and 36(44%) from group B and C were pre-diabetic, respectively. Also, no diabetics in group A while 4 (4.2%) and 5 (6.17%) from group B and C were diabetic respectively. There was a elevated incidence and prevalence of diabetes in overweight and obese patients. The multivariate analysis revealed that waist circumference has the highest validity with an AUC of 0.869, indicating a strong ability to differentiate between normal and high BMI, with a cut-off value of >90 cm, 82.95% sensitivity, and 79.41% specificity (p < 0.0001). Conclusion: The significant risk factors for prediabetes and DM that are prevalent in the population, particularly among males, have been identified in our study. BMI and waist circumference, HOMA IR, fasting insulin, and HDL are statistically significant predictors of prediabetes and diabetes. | ||
| Keywords | ||
| Egyptian Men; Diabetes; Obese; Overweight; Prediabetes | ||
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