Fungi Spectrum Evaluation, Clinical Features and Risk factors of Egyptian patients with onychomycosis in a tertiary care hospital | ||
| Zagazig University Medical Journal | ||
| Article 40, Volume 31, Issue 2, February 2025, Pages 954-962 PDF (762.09 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2024.343236.3731 | ||
| Authors | ||
| Mohammed Hamed Khater1; Shrook Abd Elshafy Khashaba2; Aya Lotfy Mohammed Abdallah* 3; Shymaa Yahia4 | ||
| 1Professor of Dermatology, Venereology, and Andrology Department, Faculty of Medicine, Zagazig university | ||
| 2Assistant professor Of Dermatology, Venereology, and Andrology Department, Faculty of Medicine, Zagazig university Department, Faculty of medicine, Zagazig University | ||
| 3MBBCH, Faculty of Medicine, Zagazig University | ||
| 4Assistant professor Of Medical Microbiology and Immunology Department, Faculty of medicine, Zagazig University | ||
| Abstract | ||
| Background: An effective treatment for onychomycosis can be achieved by identifying the etiological organism and antifungal susceptibility testing. This study aimed to isolate most prevalent fungi causing onychomycosis, detecting risk factors and clinical features of the disease. Methods: This cross-sectional prospective clinical study has been performed on 80 patients clinically diagnosed to have onychomycosis. After a careful history taking (age, sex, underlying medical conditions and possible risk factors) a nail sample was obtained and subjected to mycological examination (10% KOH microscopic examination and fungal culture for identification of causative fungi. Results: The most frequent isolated fungi were non dermatophytes which were isolated from 42.5% of the patients followed by dermatophytes in 37.5% then candida in 7.5% of the patients. The isolated non dermatophytes were A. flavus 10% A.niger10%, A.fumigatus7%, alternaria7%, scopulariopsis7% ,Cladosporium5% , Penicillium 1%. The isolated dermatophytes were T.Rubrum 20%, T.Mentagrophytes 14%, T.interdigitale 2%, E.floccosum 2%, T verrucosum 2%. Conclusion: The incidence of non-dermatophytes onychomycosis has been increasing recently. non-dermatophytes are emerging pathogens of onychomycosis among patients attending Zagazig University Hospitals. | ||
| Keywords | ||
| Fungi spectrum; Prevalence; Onychomycosis | ||
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