Intra familial Transmission of HBV in Aswan Governorate | ||
| Aswan University Medical Journal | ||
| Articles in Press, Accepted Manuscript, Available Online from 11 January 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/aumj.2025.346089.1173 | ||
| Authors | ||
| Nihal Abdel Dayem Embaby* 1; Awny Ali Abdelrahman1; Sahar Mohamed Hassany2 | ||
| 1Department of Gastroenterology and tropical Medicine, faculty of Medicine, Aswan University | ||
| 2Department of Gastroenterology and tropical Medicine, faculty of Medicine, Assuit University | ||
| Abstract | ||
| Background: Household HBV transmission is a serious health risk that affects patients, their families, and the healthcare system. As the incidence of HBV transmission within carriers' family members approaches 11–57%, a high rate of HBV infection is observed in the home contacts of chronic HBV carriers. There are errors in the precise epidemiological data about HBV in Egypt. Following the implementation of the universal baby vaccination program in 1992, Egypt's HBV prevalence rate has decreased. Aim of the study: to study the HBVs-Ag positive family members in Aswan governorate. Methods: This cross-sectional study was carried out on 50 HBV patients and their family members from gastroenterological outpatient clinic of Aswan University Hospital. Results: About one-quarter of the family members were positive for HBVs-Ag. Risk factors for HBV transmission among cases were; sexual, vertical, intravenous drug abuse while among family members were; sexual, vertical-incidence transmission, blood transfusion, intravenous drug abuse, and sharing personal items. Conclusions: The current study showed that 23% of HBV patients had family members’ infection, with positive HBsAg. Sexual and vertical transmission were the most predominant risk factors | ||
| Keywords | ||
| Hepatitis B virus (HBV); HBV PCR; HBV vaccine; HBs Ag | ||
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