Efficacy Versus Cost of Different Types of Silver Dressings on Healing of Neuropathic Diabetic Foot Ulcers | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 45, Volume 98, Issue 1, January 2025, Pages 304-310 PDF (548.02 K) | ||
| DOI: 10.21608/ejhm.2025.405467 | ||
| Abstract | ||
| Background: Wound care is essential in diabetic foot ulcers (DFUs) management. Different silver dressings are available at varied prices, but there is no agreement on which is the most cost-effective for DFU healing. Objective: This study aimed to explore the cost efficacy of existing silver dressings in healing of neuropathic DFU. Patients and methods: The study was a prospective, randomized, single center comparative, which included 60 patients with neuropathic DFUs. All patients received standard wound management. They were randomly distinct into two groups based on the type of dressing used: silver foam treatment (Mepilex® Ag) or nanocrystalline silver spray (Silver Sol®). Target was the percentage of ulcer surface area reduction after 12 weeks or complete healing. Results: Sociodemographic data and ulcer characteristics were comparable in both groups. Initial median ulcer surface area was 2.33 cm2 (0.25-5) vs. 3.0 cm2 (0.72-6.0) in foam and spray groups respectively (p=0.127). After 12 weeks, the reduction of ulcer surface area was higher among foam group (43.9 % vs. 20.3 %) (p=0.049). Complete ulcer healing was considerably higher in the foam group, 66.7 % vs. 36.7% in spray group (p = 0.02). The mean total cost of dressings per patient was considerably lower in Mepilex® group (368.0 ± 121.78 LE) than in Silver Sol® group (950.0 ± 0.0 LE) (p <0.001). Conclusions: Silver ions foam dressing is significantly more cost effective than nanocrystalline silver spray in healing of neuropathic DFUs. | ||
| Keywords | ||
| Silver ions; Silver nanoparticles; Diabetic foot ulcer | ||
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