Macular thickness in healthy subjects and diabetics without diabetic macular edema | ||
| Sohag Medical Journal | ||
| Article 23, Volume 21, Issue 1, January 2017, Pages 231-235 PDF (51.89 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/smj.2017.40747 | ||
| Authors | ||
| Mohammad Hussein Mousa1; Ali Mahmoud Ismail2; Ashraf Elhawwary3; Seham Shawky1 | ||
| 1Department of ophthalmology, Sohag faculty of medicine, Sohag University, Sohag | ||
| 2Department of Ophthalmology, Faculty of Medicine, Sohag University. | ||
| 3epartment of ophthalmology, Sohag faculty of medicine, Sohag University, Sohag | ||
| Abstract | ||
| Purpose: To compare macular thickness values in normal subjects and diabetic patients without diabetic macular edema (DME) using optical coherence tomography (OCT). Methods :comparative prospective case control study was conducted on 150 eyes with varying stages of diabetic retinopathy compared with 50 normal control. We used the Topcon,3D OCT-2000 machine to perform the fast macular scan which gives 3 concentric circles : 1 , 3 and 5 mm. centered on the fovea . The mean ± standard deviation of macular thickness by area in these eyes were analyzed and compared. Results: OCT findings demonstrated that the macula in the diabetic patients with no diabetic retinopathy group was significantly thinner than that of the control group with mean (233.34±29.15) and (221.38±24.26) respectively. In addition, our findings showed that the macular thickness with mean (221.38±24.26) ,(231.30±29.34) and (256.48 ±39.62)gradually increased with the duration of DM with mean (5.48±4.39) ,(13.96±4.93) and (14.70±4.17) respectively probably because of an increase in vascular permeability in the diabetic retinas . Conclusion: OCT will allow the detection of early changes and designing a personalized, noninvasive treatment .the role of neurodegeneration in the pathogenesis of DR is a solid basis for proposing neuroprotection as an effective strategy for preventing or arresting DR. | ||
| Keywords | ||
| OCT; diabetic retinopathy; Macular Thickness | ||
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| References | ||
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