Kamel, M., Syam, Y. (2013). Structure and physicochemical properties in relation to drug action. test, 12(2), 95-108. doi: 10.4103/1687-4315.124000
Mohsen M. Kamel; Yasmin M. Syam. "Structure and physicochemical properties in relation to drug action". test, 12, 2, 2013, 95-108. doi: 10.4103/1687-4315.124000
Kamel, M., Syam, Y. (2013). 'Structure and physicochemical properties in relation to drug action', test, 12(2), pp. 95-108. doi: 10.4103/1687-4315.124000
Kamel, M., Syam, Y. Structure and physicochemical properties in relation to drug action. test, 2013; 12(2): 95-108. doi: 10.4103/1687-4315.124000

Structure and physicochemical properties in relation to drug action

Egyptian Pharmaceutical Journal
Volume 12, Issue 2, July 2013, Pages 95-108    PDF (4.01 M)
DOI: 10.4103/1687-4315.124000
Authors
Mohsen M. Kamel; Yasmin M. Syam
Abstract

In this review, classification of drugs, chemical structure, and biological activity, examples of pharmacological activities of some structural moieties, bioisosterism, physicochemical properties in relation to drug action, drug–receptor theory, acid–base chemistry in formulation and biodistribution of the drug, quantitative structure–activity relationship, and molecular docking are briefly presented with examples.
Keywords
bioisosterism; drug distribution; Molecular modeling; Pharmacological effects; physicochemical properties
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