Abudeif, A., Galal, G., Mohammad, A., Agamy, M., Ahmad, N., Fahmy, N. (2019). VDR Gene Polymorphisms and Risk of Hepatocellular Carcinoma. test, 23(Issue 1), 24-30. doi: 10.21608/smj.2019.40879
Ahmed Abudeif; Ghada Moustafa Galal; Asmaa Naser Mohammad; Maha Mohamed Agamy; Nagwa Ahmad; Nahed Fathallah Fahmy. "VDR Gene Polymorphisms and Risk of Hepatocellular Carcinoma". test, 23, Issue 1, 2019, 24-30. doi: 10.21608/smj.2019.40879
Abudeif, A., Galal, G., Mohammad, A., Agamy, M., Ahmad, N., Fahmy, N. (2019). 'VDR Gene Polymorphisms and Risk of Hepatocellular Carcinoma', test, 23(Issue 1), pp. 24-30. doi: 10.21608/smj.2019.40879
Abudeif, A., Galal, G., Mohammad, A., Agamy, M., Ahmad, N., Fahmy, N. VDR Gene Polymorphisms and Risk of Hepatocellular Carcinoma. test, 2019; 23(Issue 1): 24-30. doi: 10.21608/smj.2019.40879

VDR Gene Polymorphisms and Risk of Hepatocellular Carcinoma

Sohag Medical Journal
Article 11, Volume 23, Issue 1, January 2019, Pages 24-30    PDF (385.53 K)
Document Type: Original Article
DOI: 10.21608/smj.2019.40879
Authors
Ahmed Abudeif1; Ghada Moustafa Galal1; Asmaa Naser Mohammad1; Maha Mohamed Agamy1; Nagwa Ahmad2; Nahed Fathallah Fahmy3
1Department of Tropical Medicine and Gastroenterology, Faculty of Medicine, Sohag University.
2Debartment of Biochemistry, Faculty of Medicine, Sohag University.
3Department of Medical Microbiology and Immunology,Faculty of Medicine, Sohag University.
Abstract
Hepatocellular carcinoma (HCC) is the sixth most common cancer in the world and the fourth most common cause of cancer death.The development of HCC is a complex and multi-factorial process, in which both environmental and genetic features interfere and contribute to malignant transformation. Numerous genetic studies have reported associations between single nucleotide polymorphisms (SNPs) and the presence of HCC.The purpose of thisreview is to describethe structure ofvitamin D receptor (VDR) gene and common polymorphisms involving it, and to address the associationsbetween VDR SNPs and cancer including HCC.
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