NADA, E., Abdo, R., Mohhmed, R., Mostafa, M. (2018). Efficacy of microneedling in treatment of acne scars. test, 22(1), 155-162. doi: 10.21608/smj.2018.40927
ESSAMELDIN ABDELAZIZ NADA; Ramadan Saleh Abdo; Rasha I. Mohhmed; Mohammed A. Mostafa. "Efficacy of microneedling in treatment of acne scars". test, 22, 1, 2018, 155-162. doi: 10.21608/smj.2018.40927
NADA, E., Abdo, R., Mohhmed, R., Mostafa, M. (2018). 'Efficacy of microneedling in treatment of acne scars', test, 22(1), pp. 155-162. doi: 10.21608/smj.2018.40927
NADA, E., Abdo, R., Mohhmed, R., Mostafa, M. Efficacy of microneedling in treatment of acne scars. test, 2018; 22(1): 155-162. doi: 10.21608/smj.2018.40927

Efficacy of microneedling in treatment of acne scars

Sohag Medical Journal
Article 17, Volume 22, Issue 1, January 2018, Pages 155-162    PDF (101 K)
Document Type: Original Article
DOI: 10.21608/smj.2018.40927
Authors
ESSAMELDIN ABDELAZIZ NADA1; Ramadan Saleh Abdo2; Rasha I. Mohhmed3; Mohammed A. Mostafa3
1Department of Dermatology , Venereology and Andrology, Faculty of Medicine , sohag university.
2Department , of Dermatology, Venereology and Andrology , Faculty of Medicine- , Sohag University.
3Department of Dermatology, Faculty of Medicine, Sohag University.
Abstract
Introduction: Microneedling is a relatively new minimally invasive procedure involving superficial and controlled puncturing of the skin by rolling with miniature fine needles.Traditionally used as a collagen induction therapy for skin rejuvenation and facial scars specially acne scars. 
Aim of the work: Evaluation of efficacy of microneedling  in treatment of acne scars.
Patients and Methods: Ten patients with post acne atrophic facial scars attending the  outpatient clinic of  Dermatology in Sohag University Hospitals between June2014 to September 2017  were offered six sessions of microneedling at an interval of 1 month.They were evaluated monthly and one month after completion of sessions for both efficacy and safety of the procedure.
Results: The mean ± SD of the patients' age in the study population were26.900±5.952years old.eight females and two males with mean acne  scars duration ± SD 8.500±6.311 years, 60% of patients had psychological distress from their acne scars. At the end of study duration Out of the ten patients 7(70%) achieved one grade reduction in their Goodman and Baron qualitative grading score while 4 patients (40% ) achieved reduction in their  quantitative ECCA " Echella d'e valuation Clinique des cicatrices d'acne" score with 8.55%  improvement in the ECCA score.  The mean  ECCA score value of V scar started to decrease earlier than U scar , but M scar was fixed up to end of sessions.
50% of patients had good satisfaction, 30% of them had very good satisfaction and only 10% had excellent satisfaction. All treated patients , had adverse events of  temporary erythema,  edema, bleeding, or a serous ooze resolving with crusting or scabbing following each session of microneedling but in 1 patient (10%) aggravation of acne occurred, bacterial infection not occurred in any of our patients.   
Conclusion: Multiple minimally invasive sessions of skin microneedling is an effective treatment for post-acne atrophic scars with the advantage of being a relatively risk-free, in-office procedure with minimal patient recovery time.
Keywords
Acne; scar; Microneedling
Supplementary Files
References

1.  Admani S, Barrio VR. Evaluation and treatment of acne from infancy to preadolescence. Dermatologic therapy. 2013;26(6):462-6.

2.  Fabbrocini G, Annunziata MC, D'Arco V, De Vita V, Lodi G, Mauriello MC, et al. Acne scars: pathogenesis, classification and treatment. Dermatology research and practice. 2010;2010:893080.

3.  Cunliffe WJ, Gould DJ. Prevalence of facial acne vulgaris in late adolescence and in adults. British medical journal. 1979;1(6171):1109-10 

4.  Midwood KS, Williams LV, Schwarzbauer JE. Tissue repair and the dynamics of the extracellular matrix. The international journal of biochemistry & cell biology. 2004;36(6):1031-7. 

5.  Kravvas G, Veitch D, Al-Niaimi F. The increasing relevance of biofilms in common dermatological conditions. The Journal of dermatological treatment. 2017:1-6. 

6.  Fernandes D. Minimally invasive percutaneous collagen induction. Oral and maxillofacial surgery clinics of North America. 2005;17(1):51-63, vi. 

7.  Doddaballapur S. Microneedling with dermaroller. Journal of cutaneous and aesthetic surgery. 2009;2(2):110-1.

 8 .  Bariya SH, Gohel MC, Mehta TA, Sharma OP. Microneedles: an emerging transdermal drug delivery system. The Journal of pharmacy and pharmacology. 2012;64(1):11-29. 

9.  Fabbrocini G, Fardella N, Monfrecola A, Proietti I, Innocenzi D. Acne scarring treatment using skin needling. Clinical and experimental dermatology. 2009;34(8):874-9.

10.       Goodman GJ, Baron JA. Postacne scarring: a qualitative global scarring grading system. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al]. 2006;32(12):1458-66.

11.       Dreno B, Khammari A, Orain N, Noray C, Merial-Kieny C, Mery S, et al. ECCA grading scale: an original validated acne scar grading scale for clinical practice in dermatology. Dermatology. 2007;214(1):46-51. 

12.       Leheta T, El Tawdy A, Abdel Hay R, Farid S. Percutaneous collagen induction versus full-concentration trichloroacetic acid in the treatment of atrophic acne scars. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al]. 2011;37(2):207-16.

13.       Sharad J. Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin. Journal of cosmetic dermatology. 2011;10(4):317-23.

14.       Gadkari R, Nayak C. A split-face comparative study to evaluate efficacy of combined subcision and dermaroller against combined subcision and cryoroller in treatment of acne scars. Journal of cosmetic dermatology. 2014;13(1):38-43.

15.       Leheta TM, Abdel Hay RM, El Garem YF. Deep peeling using phenol versus percutaneous collagen induction combined with trichloroacetic acid 20% in atrophic post-acne scars; a randomized controlled trial. The Journal of dermatological treatment. 2014;25(2):130-6. 

16.       El-Domyati M, Barakat M, Awad S, Medhat W, El-Fakahany H, Farag H. Microneedling Therapy for Atrophic Acne Scars: An Objective Evaluation. The Journal of clinical and aesthetic dermatology. 2015;8(7):36-42 

17.       Majid I. Microneedling therapy in atrophic facial scars: an objective assessment. Journal of cutaneous and aesthetic surgery. 2009;2(1):26-30.

18.       Chawla S. Split Face Comparative Study of Microneedling with PRP Versus Microneedling with Vitamin C in Treating Atrophic Post Acne Scars. Journal of cutaneous and aesthetic surgery. 2014;7(4):209-12.

19.       Dogra S, Yadav S, Sarangal R. Microneedling for acne scars in Asian skin type: an effective low cost treatment modality. Journal of cosmetic dermatology. 2014;13(3):180-7.

20.       Nofal E, Helmy A, Nofal A, Alakad R, Nasr M. Platelet-rich plasma versus CROSS technique with 100% trichloroacetic acid versus combined skin needling and platelet rich plasma in the treatment of atrophic acne scars: a comparative study. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al]. 2014;40(8):864-73. 

21.       Asif M, Kanodia S, Singh K. Combined autologous platelet-rich plasma with microneedling verses microneedling with distilled water in the treatment of atrophic acne scars: a concurrent split-face study. Journal of cosmetic dermatology. 2016;15(4):434-43.

22.       Fabbrocini G, De Vita V, Di Costanzo L, Pastore F, Mauriello MC, Ambra M, et al. Skin needling in the treatment of the aging neck. Skinmed. 2011;9(6):347-51.

23.       Singh A, Yadav S. Microneedling: Advances and widening horizons. Indian dermatology online journal. 2016;7(4):244-54.

24.       Harris AG, Naidoo C, Murrell DF. Skin needling as a treatment for acne scarring: An up-to-date review of the literature. International journal of women's dermatology. 2015;1(2):77-81.

 

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