Total Phenolic Contents and Antioxidant Activity of Pomegranate (Punica Granatum L.) Peel Extracts against Oxidative Stress Induced by Lambada Cyhalothrin Insecticides on Male Albino Rats | ||
| Egyptian Journal of Chemistry | ||
| Volume 68, Issue 1, January 2025, Pages 527-536 PDF (1.79 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2025.349994.11093 | ||
| Authors | ||
| awad Abd elfatah1; yasmin Abdel Mobdy2; Osama M. Abdel-Fatah Osama M. Abdel-Fatah3; Emam Abdelrahim4; marwa emam hassan* 5 | ||
| 1Research Institute of Medical Entomology | ||
| 2, Faculty of Agriculture, Cairo University | ||
| 3Biochemistry Department, Faculty of Agriculture, Cairo University, Egypt. | ||
| 4Biochemistry Department, Faculty of Agriculture, Cairo University, P. Box 12613, Gamma St, Giza, Egypt | ||
| 5toxicology ,research institute of medical entomology | ||
| Abstract | ||
| This study assess the pomegranate's antioxidant capacity and total phenolic content and its role as antioxidant against oxidative damages and alteration in biochemical, hematological and hormonal indices and renal and liver tissues after exposure to Lambda-cyhalothrin in experimental animals. The findings indicate that DPPH (1, 1diphenyl-2-picryl hydrazyl) and ABTS radical assays produced the strongest antioxidant activity, exceeding those of KMnO4. Pomegranate peels contain 77.09g/100g total carbohydrate, 17.08g/100g total soluble sugar, 2.27g/100g total phenols and 2.04 g/100g total flavonoids. Lambdacyhalothrin had adverse effect on human and animal, since it modifies the activities of the kidneys and liver, hematological parameters and modify the organs' histological structure. Pomegranate peels improved toxicity induced by this insecticides because pomegranate peels contain high level of antioxidant compounds. | ||
| Keywords | ||
| antioxidant activity; . Pomegranate peels; Lambdacyhalothrin; antioxidant compounds | ||
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