Hamza, H., Shabana, A., Abu shar, A., Egiz, M. (2025). Accuracy of Fetal Thigh Circumference and Fractional thigh Volume in prediction of Fetal Birth Weight. test, 29(1), 3-13. doi: 10.21608/egyfs.2025.409765
Haitham Aboali Hamza; Ayman Abd Elkader Shabana; Asmaa Mohamed Abu shar; Mahy Nabil Egiz. "Accuracy of Fetal Thigh Circumference and Fractional thigh Volume in prediction of Fetal Birth Weight". test, 29, 1, 2025, 3-13. doi: 10.21608/egyfs.2025.409765
Hamza, H., Shabana, A., Abu shar, A., Egiz, M. (2025). 'Accuracy of Fetal Thigh Circumference and Fractional thigh Volume in prediction of Fetal Birth Weight', test, 29(1), pp. 3-13. doi: 10.21608/egyfs.2025.409765
Hamza, H., Shabana, A., Abu shar, A., Egiz, M. Accuracy of Fetal Thigh Circumference and Fractional thigh Volume in prediction of Fetal Birth Weight. test, 2025; 29(1): 3-13. doi: 10.21608/egyfs.2025.409765

Accuracy of Fetal Thigh Circumference and Fractional thigh Volume in prediction of Fetal Birth Weight

The Egyptian Journal of Fertility and Sterility
Volume 29, Issue 1 - Serial Number 11106352, January 2025, Pages 3-13    PDF (252.69 K)
Document Type: Original Article
DOI: 10.21608/egyfs.2025.409765
Authors
Haitham Aboali Hamza1; Ayman Abd Elkader Shabana2; Asmaa Mohamed Abu shar* 1; Mahy Nabil Egiz2
1Department of Obstetrics and Gynecology, Faculty of Medicine, Menoufia University, Egypt
2Department of Obstetrics and Gynecology, Faculty of Medicine, Menoufia University, Egypt
Abstract
Background: Accurately estimating fetal weight facilitates optimal care planning. Traditionally, formulas using biometric parameters like the biparietal diameter (BPD) and femur length (FL) guided assessments. More recently, ultrasound measurements of the fetal thigh circumference and fractional thigh volume emerged as promising alternative predictors.   
Aim: To evaluate fetal thigh circumference & fractional thigh volume's accuracy in predicting birth weight.   
Methods: We recruited 60 women in their third trimester with singleton pregnancies, excluding cases with anomalies or gestational age discrepancies. Standardized ultrasound biometry between 37-40 weeks measured parameters including BPD, abdominal circumference (AC), head circumference (HC), FL, thigh circumference (TC) & thigh volume (TVol). Estimates utilized Hadlock's, Vintzileos', Lee formulas. Actual weights were recorded post-delivery. 
Results: The average age of participants was 29.38 ± 7.56 years. Gestational age varied among 37& 40.29 weeks. Actual birth weight mean was 3552.60 ± 689.87 grams. Estimated weights: Hadlock's - 3366.38 ± 590.82 grams, p<0.001; Vintzileos' - 3299.60 ± 630.95 grams, p=0.003; Lee 1 formula - 3693.07 ± 778.83 grams, p<0.001; Lee 2 - 3596.52 ± 754.27 grams, p=0.012. No significant variance among estimated & actual TC (pgreater than0.05). Strong positive correlations between actual weight and all estimates (p<0.001), highest for Lee 2 (r=0.985) and Lee 1 formula (r=0.984). Multiple regression identified Lee 1 and Lee 2 formula as significant predictors (p=0.040, 0.002). ROC analysis found optimal sensitivity/specificity for TVol (100/95.8%), Hadlock's (100/93.7%), Lee 1 formula (100/95.8%), Lee 2 (100/95.8%) but reduced for Vintzileos' (75/87.5%).
Conclusion: Our study revealed that Lee 2 formula proved most clinically reliable. TC and TVol also strongly correlated with actual weight, indicating reliability. TVol exhibited high diagnostic value. 

Keywords
Keywords: fetal weight estimation; thigh circumference; fractional thigh volume; gestational age; predictive accuracy
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