Alzheimer’s Disease and Diet | ||
| Egyptian Journal of Chemistry | ||
| Articles in Press, Accepted Manuscript, Available Online from 12 February 2025 | ||
| Document Type: Review Articles | ||
| DOI: 10.21608/ejchem.2025.351787.11151 | ||
| Author | ||
| Hebatalla S. Hashem* | ||
| Research on Children with Special Needs Department, Medical Research and Clinical Studies Institute, National Research Centre, Cairo, Egypt | ||
| Abstract | ||
| Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and memory impairment. While the exact cause of AD remains elusive, recent research has suggested that dietary patterns may play a significant role in its onset, progression, and management. This review explores the emerging evidence linking diet to Alzheimer’s Disease, focusing on the impact of specific nutrients and dietary patterns such as the Mediterranean diet, the ketogenic diet, and antioxidants on brain health. We examine the potential mechanisms through which diet may influence neuroinflammation, oxidative stress, amyloid-beta accumulation, and synaptic function. Furthermore, I consider the roles of essential fatty acids, vitamins, minerals, and other bioactive compounds in modulating risk factors associated with AD. The review also highlights the clinical implications and the need for further longitudinal studies to determine the efficacy of dietary interventions as part of AD prevention and management strategies. Understanding the intricate relationship between diet and AD could pave the way for new therapeutic approaches that complement pharmacological treatments and promote healthy aging. | ||
| Keywords | ||
| Alzheimer’s disease; Diet; patient | ||
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