(2024). CONVENIENT SYNTHESIS OF SOME NEW THIAZOLIDIN-4-ONE, CHROMEN-2-IMINE AND PYRROL-2-ONE DERIVATIVES CONTAINING FURAN MOIETY. test, 65(2), 46-50. doi: 10.21608/mjcc.2024.411471
. "CONVENIENT SYNTHESIS OF SOME NEW THIAZOLIDIN-4-ONE, CHROMEN-2-IMINE AND PYRROL-2-ONE DERIVATIVES CONTAINING FURAN MOIETY". test, 65, 2, 2024, 46-50. doi: 10.21608/mjcc.2024.411471
(2024). 'CONVENIENT SYNTHESIS OF SOME NEW THIAZOLIDIN-4-ONE, CHROMEN-2-IMINE AND PYRROL-2-ONE DERIVATIVES CONTAINING FURAN MOIETY', test, 65(2), pp. 46-50. doi: 10.21608/mjcc.2024.411471
CONVENIENT SYNTHESIS OF SOME NEW THIAZOLIDIN-4-ONE, CHROMEN-2-IMINE AND PYRROL-2-ONE DERIVATIVES CONTAINING FURAN MOIETY. test, 2024; 65(2): 46-50. doi: 10.21608/mjcc.2024.411471

CONVENIENT SYNTHESIS OF SOME NEW THIAZOLIDIN-4-ONE, CHROMEN-2-IMINE AND PYRROL-2-ONE DERIVATIVES CONTAINING FURAN MOIETY

Mansoura Journal of Chemistry
Volume 65, Issue 2, April 2024, Pages 46-50    PDF (1.09 M)
Document Type: Original Article
DOI: 10.21608/mjcc.2024.411471
Abstract
The attending work used Gewald's approach to produce ethyl 2-amino-4,5-diphenylfuran-3-carboxylate (2) by condensing benzoin (1) with ethyl cyanoacetate while stirring in dimethylformamide containing a catalytic amount of diethylamine. Through its interactions with practical chemical reagents, this 2-aminofuran derivative worked as a crucial synthon for the synthesis of novel thiazolidin-4-one, chromen-2-imine, and pyrrol-2-one derivatives. It was also addressed how the novel furan derivatives were achieved mechanistically
Keywords
Furan; thiazolidinone; chromene; pyrrolone; Gewald’s methodology
Statistics
Article View: 19
PDF Download: 21