Value of Myocardial Performance Index as a Parameter for Left Ventricular Cardiac Function in Heart Failure Patients | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 118, Volume 98, Issue 1, January 2025, Pages 822-827 PDF (458.26 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2025.411714 | ||
| Abstract | ||
| Background: Ejection fraction (EF) and left ventricular volumes may have significant errors due to the heart’s ellipsoidal shape becoming more spherical during dysfunction. Objective: This study aimed to evaluate the myocardial performance index (MPI) as a parameter for left ventricular function in heart failure (HF) cases. Patients and methods: This descriptive study was conducted at The Cardiovascular Medicine Department, Mansoura Specialized Internal Medicine Hospital, Mansoura University. It included 80 individuals divided into two groups: Group A (HF group) included 40 patients with HF symptoms (NYHA class 1-4) and impaired LV systolic function, selected from consecutive HF admissions. Group B (Control group) included 40 healthy adults with no cardiovascular disease, no HF symptoms (NYHA class 1), and normal echocardiography findings. Results: MPI at both septal and lateral mitral annuli was significantly higher in HF cases than in controls. A strong correlation was found between MPI values and NYHA classification. Septal MPI also correlated significantly with age and EF. ROC analysis confirmed MPI’s predictive value for HF. For lateral-MPI, AUC was 0.894 at a cut-off of 0.455, with 87.5% sensitivity, 95% specificity, 97.2% PPV, 79.2% NPV, and 90% accuracy. For septal-MPI, AUC was 0.881 at a cut-off of 0.465, with 90% sensitivity, 90% specificity, 94.7% PPV, 81.8% NPV, and 90% accuracy. Both MPI calculations showed comparable predictive value. Conclusion: MPI is a reliable predictor of LV function in HF cases. | ||
| Keywords | ||
| Myocardial performance index; Left ventricular function; Heart failure | ||
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