Laccase Immobilization on Magnetic Nanoparticles: Recent Techniques and Applications | ||
| Egyptian Journal of Chemistry | ||
| Articles in Press, Accepted Manuscript, Available Online from 23 March 2025 | ||
| Document Type: Review Articles | ||
| DOI: 10.21608/ejchem.2025.340868.10913 | ||
| Authors | ||
| Kholoud Ramadan Mohamed* 1; fatma sedeek mohamed hassan2; mohamed A. Zayed3; Mahmoud F. Mubarak4 | ||
| 1Chemistry Department, Faculty of Science, Aswan University | ||
| 2Chemistry, Faculty of Science, Aswan University, Aswan, Egypt | ||
| 3Department of chemistry, Faculty of Science, Cairo University (D.Sc. Anal.Chem.) | ||
| 4Petroleum Applications Department, Egyptian Petroleum Research Institute, Nasr City, Cairo, Egypt | ||
| Abstract | ||
| Enzyme immobilization has emerged as a powerful strategy to enhance enzyme stability, reusability, and catalytic efficiency for diverse applications, particularly in environmental remediation, such as the removal of organic pollutants from wastewater. Among various enzymes, laccases have gained significant attention for their ability to degrade a broad spectrum of organic pollutants under mild and environmentally friendly conditions. This review focuses on the immobilization of laccases onto magnetic nanoparticles as a carrier, emphasizing their advantages as robust and reusable biocatalysts for wastewater treatment. The discussion encompasses immobilization techniques, key influencing factors, and recent advancements in optimizing catalytic efficiency, thermal stability, and operational durability. Magnetic nanoparticles, with their high surface area, ease of separation, and reusability, are highlighted as ideal carriers for enzyme immobilization. Furthermore, the review critically evaluates the latest research on laccase-magnetic nanoparticle systems and challenges in scalability, cost-effectiveness, and long-term stability. Finally, the integration of these immobilized enzyme systems with complementary treatment technologies is examined as a promising avenue for sustainable and efficient pollution control strategies. | ||
| Keywords | ||
| Biological activity; catalytic efficiency; chemical immobilization; enzymes; immobilization techniques; physical immobilization | ||
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