Screening of Von Willebrand Disease Among Children with Severe or Recurrent Attacks of Epistaxis. | ||
| Benha Journal of Applied Sciences | ||
| Articles in Press, Accepted Manuscript, Available Online from 27 March 2025 | ||
| Document Type: Original Research Papers | ||
| DOI: 10.21608/bjas.2025.363342.1598 | ||
| Authors | ||
| Ghada Saad Abdelmotaleb1; Ahmed Ashraf El Hamshary2; Amira Mohamed3; Aliaa Diab4; Eman Hamada Taha* 5 | ||
| 1Professor of Pediatrics Faculty of Medicine-Benha University | ||
| 2Professor of Otorhinolaryngiology Faculty of Medicine-Benha University | ||
| 3Assistant Professor of Clinical and chemical pathology Faculty of Medicine-Benha University | ||
| 4Lecturer of Pediatrics Faculty of Medicine - Benha University | ||
| 5Department of Pediatrics Faculty of Medicine-Benha University | ||
| Abstract | ||
| Mild mucosal bleeding is the hallmark of von Willebrand disease (VWD), a congenital bleeding illness caused by a malfunction or deficit of von Willebrand factor (VWF). Von Willebrand disease is a prevalent but underappreciated bleeding ailment; our study's objective was to assess infants with severe or recurring epistaxis for the likelihood of this disorder. Methods and Patients: A total of seventy children who presented to the emergency room or outpatient clinic with epistaxis were included in this cross-sectional research. Complete blood counts, PTs, APTTs, VWF Ag, and VWF activities were among the blood assays performed on all patients in addition to clinical examinations and history gathering. One patient was found to have VWD out of seventy who presented with severe or recurring epistaxis over the course of the research. In conclusion, children experiencing severe or recurring epistaxis should be evaluated for VWD. Topics: Epistaxis in Children with Von Willebrand Disease. | ||
| Keywords | ||
| VWD; PTs; APTTs; VWF | ||
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