Nasal Microbiome Profile of Healthy Subjects | ||
| Records of Pharmaceutical and Biomedical Sciences | ||
| Volume 9, Issue 2, March 2025, Pages 8-14 PDF (467.85 K) | ||
| Document Type: Mini-reviews | ||
| DOI: 10.21608/rpbs.2025.358243.1354 | ||
| Authors | ||
| Samah El-Sayed Hamed* 1; Amro Hanora2; Salah Abdallah3; Shymaa Enany4 | ||
| 1Demonstrator of Microbiology and Immunology, Faculty of Pharmacy, Suez Canal University, | ||
| 2-Professor of Microbiology and Immunology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt. -Professor of Microbiology & Immunology, Faculty of Pharmacy, King Salman International University, Ras Sudr, Egypt. | ||
| 3Professor of Microbiology and Immunology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt. | ||
| 4department of microbiology and immunology, faculty of pharmacy, Ismailia, Egypt | ||
| Abstract | ||
| The nasal passages' microbial communities are vital to human health and can significantly influence infection processes. The nasal microbiome can be changed by environmental factors such the style of delivery, the kind of milk feeding, the use of antibiotics, and particular diets, which can disrupt the organization of the microbiome community. Therefore, it is essential to identify nasal microbiota and the relationships between community members to prevent and cure a variety of respiratory illnesses. A remarkable diversity in the nasal passages’ microbiota was observed. The taxonomy in the healthy nasal microbiome recognized four major phyla, including Actinobacteria, Firmicutes, Proteobacteria, and Bacteroidetes, with little variation in abundance. Corynebacterium and Dolosigranulum, the most predominant genera, showed the highest relative abundance. It is hypothesized that the environmental factors may change the nasal microbiome, consequently disrupting its community structure. These findings highlight the potential clinical and public health consequences of nasal microbiome particularly in healthy people. | ||
| Keywords | ||
| Metagenomics sequencing; nasal passages microbiome; shotgun | ||
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