Randomized Controlled Clinical Study Evaluating Dental Implant Primary Stability, Radiographic Bone Density and Osteopontin Expression in the Regenerated Alveolar Bone in Post-Extraction Sockets Treated with Vitamin D3 | ||
| Egyptian Dental Journal | ||
| Volume 71, Issue 2 - Serial Number 3, April 2025, Pages 1401-1416 PDF (2.53 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/edj.2025.359006.3378 | ||
| Authors | ||
| AHMED ELSAYED HAMED AMR* 1; Raghdaa Mostafa2; Shaimaa Ghazy3 | ||
| 1Associate Professor of Oral Medicine and Periodontology, Faculty of Dentistry, Ain Shams University | ||
| 2Associate Professor of Oral and Maxillofacial Radiology, Faculty of Dentistry, Ain Shams University | ||
| 3Associate Professor of Oral Pathology, Faculty of Dentistry, Ain Shams University | ||
| Abstract | ||
| Purpose of the study: Evaluating the influence of combination of vitamin D3 with particulate bovine xenograft when placed in post-extraction sockets on the newly formed bone quality. Primary outcome: Implant primary stability Secondary outcomes: Radiographic bone density and immunohistochemical expression of osteopontin in newly formed regenerated bone Subjects and methods: Patient with non-restorable maxillary anterior tooth or single root premolar that require extraction and dental implant. Test group: 13 extraction sites received particulate xenograft mixed with vitamin D3. Control group: 13 extraction sites received particulate xenograft alone. After 6 months implants were placed. Implant primary stability, radiographic bone density, immunohistochemical osteopontin expression in grafted sites were evaluated. Results: A significantly higher mean value of both primary stability and bone density were recorded in test group. Conclusion: Taking in considerations the limitations of the current study, the addition of vitamin D to particulate xenogenic bone graft enhanced newly formed bone density, implant stability and is associated with increased expression of OPN level in grafted sites. | ||
| Keywords | ||
| Tooth Socket; Vitamin D; augmentation | ||
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