Antibiotic Resistance Patterns of Uropathogens in Long Term Care Facilities | ||
| The Egyptian Journal of Geriatrics and Gerontology | ||
| Article 1, Volume 4, Issue 2, October 2017, Pages 1-5 PDF (1.03 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejgg.2017.5052 | ||
| Author | ||
| EL Bedewy RMS* | ||
| Geriatrics & Gerontology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt. | ||
| Abstract | ||
| Background: Residence at a Long term care faci l i ty (LTCF) and older age are both recognized as signi ficant risk factors for harboring mul tidrug resistant Gram-negative bacteria (MDRGNB) Aim: The objective of this descriptive study is to detect the commonest mul tidrug resistant bacteria and i ts antibiotic sensi tivi ty in urine of elderly residents at LTCF wi th urinary t ract infection (UTI ) . Methods: Eighty one LTCF elderly residents wi th UTI. Cul ture and sensi tivi ty was done for urine samples documenting mul tidrug resistant organisms wi th antibiotic susceptibi l i ty to a range of di f ferent antibiotic groups. Demographic data was col lected and comorbidi ties were establ ished. Al l samples were processed as per standard techniques and bacteria identi fied by standard biochemical tests. IBM SPSS statistics (version 24, IBM corp., USA, 2016) was used for data analysis. Results: The age ranges f rom 60 to 90 years wi th mean 69.86 +/ - 9.68 years Males are 74.1% whi le females are 25.9 %. The predominant resistant detected organism in these samples was Proteus (58.0%) then E col i (19.8 %), Klebsiela (18.5 %) then Pseudomonas (3.7 %). Proteus is found to be highly statistical ly signi ficant sensi tive to Cefepime (CPM), Ciprofloxacin (CP), and Imipenam ( IMP) and to be highly statistical ly signi ficant resistant to Col istin (CT), Gentamycin (GM) , Tobramycin (Tobra. ), Ni trofurantoin (FD) , and Trimethoprim/Sul famethoxazole (TS). E Col i is found to be highly statistical ly signi ficant sensi tive to Col istin (CT), Trimethoprim/ Sul famethoxazole (TS), Gentamycin (GM), Tobramycin(Tobra. ) and Ni trofurantoin (FD) and resistant to Cefepime (CPM) . Further studies are recommended on larger numbers of elderly patients to confi rm or not confi rm signi ficant findings in this study, t ry to explain these findings, and make use of i t in cl inical practice. Conclusion: Proteus is the commonest mul ti resistant uropathogen in those under 70 years whi le psuedomonas is the most prevalent one in elderly between71 -90 years of age | ||
| Keywords | ||
| Antibiotic susceptibi l i ty; mul ti drug resistant bacteria; urine; UTI; long term care faci l i ty; Elderly | ||
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