EVALUATION OF SERUM 25-HYDROXYVITAMIN D IN CHILDREN WITH CHRONIC KIDNEY DISEASE ON DIALYSIS AT ZAGAZIG UNIVERSITY CHILDREN HOSPITALS | ||
| Zagazig University Medical Journal | ||
| Article 243, Volume 27, Issue 3, May 2021, Pages 439-446 PDF (627.38 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2019.15643.1400 | ||
| Authors | ||
| Ays Ahmed Ragaey* 1; Ali Mohammed Abo Zaid1; Seham Fathy Azab1; Asmaa Mohammed Osh2 | ||
| 1Pediatrics Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt | ||
| 2Clinical Pathology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt | ||
| Abstract | ||
| ABSTRACT Background: Vitamin D deficiency and insufficiency in chronic kidney disease (CKD) patients on dialysis is associated with undesirable outcomes as rapid progression to later stages of renal insufficiency, and greater risk of mortality. At the mean time data is limited regarding if vitamin D deficiency and insufficiency is more present in children with chronic kidney disease on dialysis or not. Subjects and Methods: In this cross sectional study, 42 pediatric patients aged from 3-16 years with CKD on dialysis were enrolled, Serum serum 25-hydroxyvitamin D (25(OH)D) levels were determined by enzyme-linked immunosorbent assay (ELISA). Results: Out of 42 pediatric patients, 71.4% of the patients had 25(OH)D deficiency, 26.2% had vitamin D insufficiency and only 2.4% were vitamin D sufficient. 25(OH)D insufficiency and deficiency is more prevalent in more severe cases of CKD and also more prevalent in children with longer duration of dialysis. Conclusion: CKD patients on dialysis therapy are more likely to have 25(OH)D deficiency or insufficiency, vitamin D deficiency and insufficiency increase by increasing the severity of CKD and increasing the duration of dialysis. Keywords: Vitamin D, chronic kidney disease, dialysis. | ||
| Keywords | ||
| Vitamin D; Chronic Kidney Disease; dialysis | ||
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