Amer, S., Maatouq, A., Ahmed, H., Hassan, E. (2020). Evaluation for Efficacy of Commercially Available Vaccines Against Challenge with Newcastle Disease Virus Genotype VII in Broilers. test, 51(1), 35-41. doi: 10.21608/ejvs.2019.14003.1088
Sameh Abdel-Moez Amer; Asmaa Mahmoud Maatouq; Hager Magdy Ahmed; Eman Ramadan Hassan. "Evaluation for Efficacy of Commercially Available Vaccines Against Challenge with Newcastle Disease Virus Genotype VII in Broilers". test, 51, 1, 2020, 35-41. doi: 10.21608/ejvs.2019.14003.1088
Amer, S., Maatouq, A., Ahmed, H., Hassan, E. (2020). 'Evaluation for Efficacy of Commercially Available Vaccines Against Challenge with Newcastle Disease Virus Genotype VII in Broilers', test, 51(1), pp. 35-41. doi: 10.21608/ejvs.2019.14003.1088
Amer, S., Maatouq, A., Ahmed, H., Hassan, E. Evaluation for Efficacy of Commercially Available Vaccines Against Challenge with Newcastle Disease Virus Genotype VII in Broilers. test, 2020; 51(1): 35-41. doi: 10.21608/ejvs.2019.14003.1088

Evaluation for Efficacy of Commercially Available Vaccines Against Challenge with Newcastle Disease Virus Genotype VII in Broilers

Egyptian Journal of Veterinary Sciences
Article 4, Volume 51, Issue 1, April 2020, Pages 35-41    PDF (1.2 M)
Document Type: Original Article
DOI: 10.21608/ejvs.2019.14003.1088
Authors
Sameh Abdel-Moez Amer* 1; Asmaa Mahmoud Maatouq2; Hager Magdy Ahmed3; Eman Ramadan Hassan2
1Department of Poultry Diseases, Veterinary Research Division, National Research Centre, P.O. Code 12622, Dokki, Cairo, Egypt..
2Department of Poultry Diseases, Veterinary Research Division, National Research Centre, P.O. Code 12622, Dokki, Cairo, Egypt.
3Poultry and Rabbit disease Department, Veterinary Research Division, NRC
Abstract
The study evaluated the protective efficacy of commercially available live and inactivated Newcastle Disease Virus (NDV) vaccines. Moreover, study also highlighted the implementation of genotypically-matched NDV vaccines to the currently circulated velogenic genotype VII strain in commercial broilers vaccination regimes in Egypt. Serum antibodies level was assessed by Haemagglutination Inhibition method .Efficacy of Newcastle Disease killed and live vaccine was also determined using challenge test. Group A immunized with live attenuated and inactivated NDV vaccines genotype VII homologous to challenge virus provided non-significant protection against mortality .It proved 20 % as compared to 15 % mortalities in group B immunized with live attenuated and inactivated NDV vaccines genotype II heterologous to challenge virus. Meanwhile, group Aredult proved a significant reduction in viral shedding by cloacal swabs in compared with group B ,7 days post-challenge. Final Results of the present work concluded that live and inactivated NDV genotype VII vaccines antigenically matched to currently epidemic NDV genotype VII providing better control on virus shedding if compared with different genotype II vaccines.  However, both vaccines provided good protection against likely virulent challenge in commercial broilers.
Keywords
vaccines; Newcastle; Disease Virus; Broilers; genotype VII
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