Eosinophilic ascites: Uncommon Presentation of Eosinophilic Gastroenteritis in children | ||
| Medical Journal of Viral Hepatitis | ||
| Article 1, Volume 3.2, Issue 2, April 2019, Pages 37-40 PDF (48.1 K) | ||
| Document Type: Research articles | ||
| DOI: 10.21608/mjvh.2018.55725 | ||
| Authors | ||
| Elhadidy Abdelmoneim1; Farid Khaled2 | ||
| 1Gastroetetro- and Hepatology dept., Damietta fever hospital, Egypt | ||
| 2Tropical Medicine dept, Faculty of Medicine, Mansoura Univ., Egypt. | ||
| Abstract | ||
| Eosinophilic gastroenteritis (EGE) is a rare condition characterized by eosinophilic infiltration of the gastrointestinal tract. It is classified into mucosal, muscular, and sub-serosal types, depending on the clinical picture and the depth of eosinophilic infiltration within the gastrointestinal wall. Sub-serosal type, the most uncommon variant, which is complicated by ascites and peripheral hypereosinophilia, usually results in the most severe clinical form of eosinophilic gastroenteritis and requires early therapy. The clinical features are non-specific with history of atopic predisposition and allergy. Endoscopic biopsy is frequently non-diagnostic due to an uninvolved gastrointestinal mucosa rendering its diagnosis a challenge. The backbone of diagnosis is peripheral hypereosinophilia and eosinophil-rich ascitic fluid on diagnostic paracentesis. Oral steroid therapy is usually the first line of treatment with dramatic response. Due to a propensity for relapse, steroid-sparing therapy should be considered for relapses of EGE. We report a case of subserosal EGE with diagnostic clinical features and treatment response and review the current strategy in the management of eosinophilic ascites. | ||
| Keywords | ||
| Eosinophilic gastroenteritis; hypereosinophilia; steroid therapy | ||
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