Spontaneous Bacterial Peritonitis: An Overview | ||
| Medical Journal of Viral Hepatitis | ||
| Article 3, Volume 3.1, Issue 1, November 2018, Pages 13-17 PDF (220.07 K) | ||
| Document Type: Review articles | ||
| DOI: 10.21608/mjvh.2018.55751 | ||
| Authors | ||
| Samir Amr; Abdel-Razik Ahmed; Elgamal Hoda | ||
| Tropical Medicine dept, Faculty of Medicine, Mansoura Univ., Egypt | ||
| Abstract | ||
| Spontaneous bacterial peritonitis (SBP) is a risky complication that occurs amongst cirrhotic patients with ascites. SBP develops in approximately 10 to 30% and has an estimated inhospital mortality rate of 20%. SBP outcomes from translocation of bacteria from the intestinal lumen. Also, SBP results from a bacteremia that initiates at a distant site, such as a urinary tract infection. The majority of cases of SBP are produced by gram-negative enteric organisms, such as Escherichia coli and Klebsiella pneumonia. Third-generation, broad-spectrum cephalosporins continue a good initial choice for SBP treatment. Levofloxacin is an acceptable alternative for patients not receiving long-term flouroquinolone prophylaxis or for those with a penicillin allergy. Different antibiotics such as pipercillintazobactam should be considered for patients with nosocomial SBP or for patients who fail to improve on traditional antibiotic regimens. | ||
| Keywords | ||
| Spontaneous Bacterial Peritonitis; Cirrhosis; Ascites and gram-negative enteric organisms | ||
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