AI-Shabrawey, M., Amer, M. (2004). EFFECT OF SHORT VERSUS LONG -TERM DIABETES ON ISCHEMIC HEART OF EXPERIMENTAL ANIMALS. test, 27(1), 25-41. doi: 10.21608/ejana.2004.5895
Mohamed AI-Shabrawey; Maged Amer. "EFFECT OF SHORT VERSUS LONG -TERM DIABETES ON ISCHEMIC HEART OF EXPERIMENTAL ANIMALS". test, 27, 1, 2004, 25-41. doi: 10.21608/ejana.2004.5895
AI-Shabrawey, M., Amer, M. (2004). 'EFFECT OF SHORT VERSUS LONG -TERM DIABETES ON ISCHEMIC HEART OF EXPERIMENTAL ANIMALS', test, 27(1), pp. 25-41. doi: 10.21608/ejana.2004.5895
AI-Shabrawey, M., Amer, M. EFFECT OF SHORT VERSUS LONG -TERM DIABETES ON ISCHEMIC HEART OF EXPERIMENTAL ANIMALS. test, 2004; 27(1): 25-41. doi: 10.21608/ejana.2004.5895

EFFECT OF SHORT VERSUS LONG -TERM DIABETES ON ISCHEMIC HEART OF EXPERIMENTAL ANIMALS

The Egyptian Journal of Anatomy
Article 2, Volume 27, Issue 1, January 2004, Pages 25-41    PDF (1.3 M)
Document Type: Original Article
DOI: 10.21608/ejana.2004.5895
Authors
Mohamed AI-Shabrawey1; Maged Amer2
1Anatomy Departments, Faculty of Medicine, Mansoura University
2Cardiology Departments, Faculty of Medicine, Mansoura University
Abstract
Coronary artery disease is a major complication of diabetes that correlates with high morbidity and mortality after myocardial infarction (Abbud et aI., 1995). Experimental studies of diabetes effects on ischemia/ reperfusion injury have shown contradictory results, inclUding a decrease, (Feuvray and Lopaschuk, 1997) increase (Paulson, 1997) or no change
(Pijl et aI., 1994) in sensitivity. These contradictory results appear to be due to differences in the duration and severity of the diabetic state. Studies have shown that the diabetic heart is resistant to ischemia/reperfusion injury during early phases of the disease, and becomes more sensitive to ischemia/reperfusion injury as the disease progresses (Ravingerova et al., 2003; Xu et al., 2004).
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