EFFECT OF NICOTINE ON SPERMATOGENESIS IN ADULT ALBINO RAT | ||
| The Egyptian Journal of Anatomy | ||
| Article 3, Volume 27, Issue 1, January 2004, Pages 43-66 PDF (2.98 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejana.2004.5896 | ||
| Authors | ||
| Wafik Nesseim; Heshmat Haroun; Mohamed Mostafa; Magdy Youakim | ||
| Anatomy Department, Faculty of Medicine, Cairo University | ||
| Abstract | ||
| Spermatogenesis is affected by many factors including smoking, as it causes fall in primary spermatocyte number, retardation of conversion of spermatocytes to spermatids in rats, as well as several morphologic abnormalities of sperms such as bicephalia (Kulikauskas et aI., 1985). Experimental evidence from humans and rodents suggested that nicotine, the most characteristic component of tobacco, could alter the hypothalamic-hypo-physeal axis through its stimulation of growth hormone, cortisol, vasopressin and oxytocin release which in turn inhibits the release of luteinizing hormone and prolactin (Weisberg, 1985). | ||
| Keywords | ||
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