EVALUATION OF TOPICAL OZONE THERAPY ON HEALING OF MANDIBULAR BONY DEFECTS | ||
| Alexandria Dental Journal | ||
| Article 3, Volume 40, Issue 2, December 2015, Pages 148-152 PDF (1.22 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/adjalexu.2015.59133 | ||
| Authors | ||
| S.T Mohamed* ; A.A Sharara* ; H.R Ragab* ; N.M Zahran* | ||
| B.D.S. Faculty of Dentistry, Alexandria University | ||
| Abstract | ||
| Introduction: Bone defects are commonly found in oral cavity, they may have functional or esthetical problems that need surgical intervention. The emergence of ozone therapy seems to be a promising future in different dental modalities that may be effective in treating bony defects. Objective: To evaluate histologically the effect of topical administration of ozone therapy; on healing of experimentally-induced mandibular bone defects; in dogs. Materials and methods: A split mouth design was carried out below the 4th mandibular premolar of six healthy mongrel dogs. A total of 12 bony defects were surgically created. After reflecting the mucoperiosteal flap, the defects in the right side were treated with ozonated gel and those in the left side did not receive any treatment. Two dogs were sacrificed after 2, 6, 12 weeks. Samples were dissected and prepared for histological evaluation Results: The study revealed that using ozone gel in bony mandibular defects accelerates the onset of new bone formation and increases vascularization at the injured site. Conclusion: Ozone is a beneficial agent to avoid possible complications and to have better chance for soft and hard tissue healing. | ||
| Keywords | ||
| Ozone gel; bony defect; Histological examination | ||
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