Zaghary, W., El-Azzouny, A., Motaleb, M., Kedr, M. (2005). SYNTHESIS OF SOME PYRIMIDINE DERIVATIVES OF EXPECTED BIOLOGICAL ACTIVITIES. test, 28(1), 17-25. doi: 10.21608/bfsa.2005.64886
Wafaa A. Zaghary; Aida A. El-Azzouny; Mohammed A. Motaleb; Mohammed A. Kedr. "SYNTHESIS OF SOME PYRIMIDINE DERIVATIVES OF EXPECTED BIOLOGICAL ACTIVITIES". test, 28, 1, 2005, 17-25. doi: 10.21608/bfsa.2005.64886
Zaghary, W., El-Azzouny, A., Motaleb, M., Kedr, M. (2005). 'SYNTHESIS OF SOME PYRIMIDINE DERIVATIVES OF EXPECTED BIOLOGICAL ACTIVITIES', test, 28(1), pp. 17-25. doi: 10.21608/bfsa.2005.64886
Zaghary, W., El-Azzouny, A., Motaleb, M., Kedr, M. SYNTHESIS OF SOME PYRIMIDINE DERIVATIVES OF EXPECTED BIOLOGICAL ACTIVITIES. test, 2005; 28(1): 17-25. doi: 10.21608/bfsa.2005.64886

SYNTHESIS OF SOME PYRIMIDINE DERIVATIVES OF EXPECTED BIOLOGICAL ACTIVITIES

Bulletin of Pharmaceutical Sciences Assiut University
Article 3, Volume 28, Issue 1, June 2005, Pages 17-25    PDF (188.55 K)
Document Type: Original Article
DOI: 10.21608/bfsa.2005.64886
Authors
Wafaa A. Zaghary1; Aida A. El-Azzouny2; Mohammed A. Motaleb3; Mohammed A. Kedr1
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt
2Department of Pharmaceutical Sciences, National Research Center, Dokki, Giza
3Hot Labs. Center, Atomic Energy Authority, Cairo, Egypt
Abstract
A series of 4-substituted pyrimidines and fused pyrimidine ring system e.g. pyrido[2,3-d] pyrimidine were synthesized and the antitumor activity have been carried out for 8 compounds. Compound 4a also, which carries the pharmacophoric group IDA was tested for the hepatobilliary imaging effect.
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