Haggag, E., Laatsch, H. (2004). BIOTRANSFORMATION OF INDOLE ALKALOID BY TERRESTRIAL STREPTOMYCES GW 14/587 STRAIN INTO A SELECTIVE PHYCOTOXIC AGENT. test, 27(1), 113-122. doi: 10.21608/bfsa.2004.65420
E. G. Haggag; H. Laatsch. "BIOTRANSFORMATION OF INDOLE ALKALOID BY TERRESTRIAL STREPTOMYCES GW 14/587 STRAIN INTO A SELECTIVE PHYCOTOXIC AGENT". test, 27, 1, 2004, 113-122. doi: 10.21608/bfsa.2004.65420
Haggag, E., Laatsch, H. (2004). 'BIOTRANSFORMATION OF INDOLE ALKALOID BY TERRESTRIAL STREPTOMYCES GW 14/587 STRAIN INTO A SELECTIVE PHYCOTOXIC AGENT', test, 27(1), pp. 113-122. doi: 10.21608/bfsa.2004.65420
Haggag, E., Laatsch, H. BIOTRANSFORMATION OF INDOLE ALKALOID BY TERRESTRIAL STREPTOMYCES GW 14/587 STRAIN INTO A SELECTIVE PHYCOTOXIC AGENT. test, 2004; 27(1): 113-122. doi: 10.21608/bfsa.2004.65420

BIOTRANSFORMATION OF INDOLE ALKALOID BY TERRESTRIAL STREPTOMYCES GW 14/587 STRAIN INTO A SELECTIVE PHYCOTOXIC AGENT

Bulletin of Pharmaceutical Sciences Assiut University
Article 14, Volume 27, Issue 1, June 2004, Pages 113-122    PDF (521.94 K)
Document Type: Original Article
DOI: 10.21608/bfsa.2004.65420
Authors
E. G. Haggag1; H. Laatsch2
1Department of Pharmacognosy, Faculty of Pharmacy, Helwan University at Ain Helwan, Cairo, 11795 Egypt
2Department of Organic Chemistry, George-August-University, Tammann Strasse 2, Gottingen, 27570, Germany
Abstract
Methyl indole was isolated as a metabolite from the culture broth of terrestrial Streptomyces GW 14/587 strain which was fed with indole after two days growth and then inoculated for another two, three and four days to optimize the experiment condition for highest metabolite concentration. The structure of the isolated methyl indole was established using spectral techniques of HPLC-MS, EI-MS, 1H and 13CNMR. Also the bacterial extract showed a high selective phycotoxic activity against Scendensmus subspicatus among the different tested microalgae, yeast, fungi and bacteria.
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