Synthesis of Dibenzofuran Derivatives Possessing Anticancer Activities: A Review | ||
| Egyptian Journal of Chemistry | ||
| Article 27, Volume 63, Issue 6, June 2020, Pages 2355-2367 PDF (1.32 M) | ||
| Document Type: Review Articles | ||
| DOI: 10.21608/ejchem.2020.21937.2310 | ||
| Authors | ||
| Gaber Osman Mohamed Moustafa* 1; Asma S. Al-Wasidi2; Ahmed M. Naglah3; Moamen Refat4 | ||
| 1El-Tahreer str 456 | ||
| 2Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia | ||
| 3Peptide Chemistry Department, Chemical Industries Research Division, National Research Centre, 12622- Dokki, Cairo, Egypt | ||
| 4Taif University | ||
| Abstract | ||
| This review focuses on reports concerning the isolation and/or synthesis of dibenzofuran derivatives’ isolation and synthesis (whether one of them or both occurs simultaneously) existing naturally while exhibiting evident biological anticancer activity. While not a comprehensive approach to all relevant compounds, the review intends to demonstrate anticancer activity’s reach related to said compounds instead and the various natural origins and synthetic methods from which and by which the compounds are to be secluded and prepared. Compounds with reduced benzene rings, e.g., morphine as well as its derivatives, are omitted, same for compounds with aromaticity disrupted by alkylation, as with usnic acid. | ||
| Keywords | ||
| dibenzofuran derivatives; Anticancer activities; polychlorinated dibenzo-p-dioxins; polychlorinated biphenyl | ||
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