Dranik, L., Dolganenko, L., Grysodub, A., Levin, M., Eshami, I. (1992). A PRELIMINARY INVESTIGATION OF FLAVANOLIGNANS OF SILYBUM MARIANUM (L) GEARTN FRUITS GROWING IN EGYPT. test, 15(1), 22-26. doi: 10.21608/bfsa.1992.70209
L. Dranik; L. Dolganenko; A. Grysodub; M. Levin; I. M. Eshami. "A PRELIMINARY INVESTIGATION OF FLAVANOLIGNANS OF SILYBUM MARIANUM (L) GEARTN FRUITS GROWING IN EGYPT". test, 15, 1, 1992, 22-26. doi: 10.21608/bfsa.1992.70209
Dranik, L., Dolganenko, L., Grysodub, A., Levin, M., Eshami, I. (1992). 'A PRELIMINARY INVESTIGATION OF FLAVANOLIGNANS OF SILYBUM MARIANUM (L) GEARTN FRUITS GROWING IN EGYPT', test, 15(1), pp. 22-26. doi: 10.21608/bfsa.1992.70209
Dranik, L., Dolganenko, L., Grysodub, A., Levin, M., Eshami, I. A PRELIMINARY INVESTIGATION OF FLAVANOLIGNANS OF SILYBUM MARIANUM (L) GEARTN FRUITS GROWING IN EGYPT. test, 1992; 15(1): 22-26. doi: 10.21608/bfsa.1992.70209

A PRELIMINARY INVESTIGATION OF FLAVANOLIGNANS OF SILYBUM MARIANUM (L) GEARTN FRUITS GROWING IN EGYPT

Bulletin of Pharmaceutical Sciences Assiut University
Article 3, Volume 15, Issue 1, 1992, Pages 22-26    PDF (183.75 K)
Document Type: Original Article
DOI: 10.21608/bfsa.1992.70209
Authors
L. Dranik1; L. Dolganenko1; A. Grysodub1; M. Levin1; I. M. Eshami2
1All-Union Research Institute of Drug Chemistry and Technology, Kharkov, USSR
2Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt
Abstract
The flavanolignans of the fruits were isolated by column chromatography and identified by TLC and HPLC in addition to m.p., ms, uv and optical rotation measurements. A comparative study by TLC and HPLC of the flavanolignans from the purple flowered and the white-flowered plants of Silybum marianum  was performed. The major flavanolignans of the white flowered plants were identified as silybin, silychristin, silydianin and taxipholin. The major flovanolignans of purple-f lowered plants were found to be silybin, silichristin and taxipholin.
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