ROLE OF BOSWELLIC ACID IN THE TREATMENT OF PEPTIC ULCER DISEASE | ||
| Al-Azhar Journal of Pharmaceutical Sciences | ||
| Article 10, Volume 60, Issue 2, September and October 2019, Pages 122-145 PDF (576.54 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ajps.2019.70246 | ||
| Author | ||
| Mai Sherif* | ||
| MaiMohie@outlook.com | ||
| Abstract | ||
| A peptic ulcer is a chronic disease. Its main features are the incompetent defense of the mucosal and the existence of the gastric juice. The two most important factors that disrupt the balance between the acid and the mucus are the Helicobacter pylori infection (H. pylori) and Non-steroidal anti-inflammatory drugs (NSAIDs). The known treatments like proton pump inhibitors (PPIs) and histamine-2 (H2) receptor antagonists have demonstrated adverse effects and various drug interactions. So the desired approach nowadays is alternative therapies and the usage of herbal products. Boswellic acids provide a potential alternative to the treatment of non-steroidal anti-inflammatory drugs induced peptic ulcer. | ||
| Keywords | ||
| Peptic ulcer; Boswellic acid; matrix metalloproteinase; Indomethacin; antioxidant | ||
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