Kh. Hameed, B., M. Fadhil, R., Sh. Hussain, R., A. Abdullah, B., A. Hadi, K., S. Obid, W., H. Hadree, D., A. Gabori, E., E. Mustafa, N. (2019). Effect of Metamizole (Dipyrone) on Blood and Histological Pictures of Liver and Spleen in Rats. test, 50(The 8th lnternational Conference of Veterinary Research Division (NRC) Cairo, Egypt , 3rd-5th December, 2019), 89-94. doi: 10.21608/ejvs.2020.19551.1126
B. Kh. Hameed; R. M. Fadhil; Rasha Sh. Hussain; Buthina A. Abdullah; Kh. A. Hadi; Wassan S. Obid; D. H. Hadree; Enaam A. Gabori; Nadya E. Mustafa. "Effect of Metamizole (Dipyrone) on Blood and Histological Pictures of Liver and Spleen in Rats". test, 50, The 8th lnternational Conference of Veterinary Research Division (NRC) Cairo, Egypt , 3rd-5th December, 2019, 2019, 89-94. doi: 10.21608/ejvs.2020.19551.1126
Kh. Hameed, B., M. Fadhil, R., Sh. Hussain, R., A. Abdullah, B., A. Hadi, K., S. Obid, W., H. Hadree, D., A. Gabori, E., E. Mustafa, N. (2019). 'Effect of Metamizole (Dipyrone) on Blood and Histological Pictures of Liver and Spleen in Rats', test, 50(The 8th lnternational Conference of Veterinary Research Division (NRC) Cairo, Egypt , 3rd-5th December, 2019), pp. 89-94. doi: 10.21608/ejvs.2020.19551.1126
Kh. Hameed, B., M. Fadhil, R., Sh. Hussain, R., A. Abdullah, B., A. Hadi, K., S. Obid, W., H. Hadree, D., A. Gabori, E., E. Mustafa, N. Effect of Metamizole (Dipyrone) on Blood and Histological Pictures of Liver and Spleen in Rats. test, 2019; 50(The 8th lnternational Conference of Veterinary Research Division (NRC) Cairo, Egypt , 3rd-5th December, 2019): 89-94. doi: 10.21608/ejvs.2020.19551.1126

Effect of Metamizole (Dipyrone) on Blood and Histological Pictures of Liver and Spleen in Rats

Egyptian Journal of Veterinary Sciences
Article 11, Volume 50, The 8th lnternational Conference of Veterinary Research Division (NRC) Cairo, Egypt , 3rd-5th December, 2019, December 2019, Pages 89-94    PDF (2.21 M)
Document Type: Original Article
DOI: 10.21608/ejvs.2020.19551.1126
Authors
B. Kh. Hameed1; R. M. Fadhil2; Rasha Sh. Hussain3; Buthina A. Abdullah2; Kh. A. Hadi* 2; Wassan S. Obid2; D. H. Hadree2; Enaam A. Gabori4; Nadya E. Mustafa5
1Department of Anatomy and Histology, Veterinary Medicine faculty, Tikrit University, Tikrit, Iraq.
2Department of Physiology, Pharmacology and Biochemistry, Veterinary Medicine faculty, Tikrit University, Tikrit, Iraq.
3Department of Biology, Faculty of Education for Pure Science, Tikrit University, Tikrit, Iraq.
4Department of Medical Laboratory Technique, Al-noor University College, Mosul, Iraq.
5General Directorate for Education of Kirkuk, Ministry of education, Iraq.
Abstract
We used in our study Twenty rats ,divided into two  groups .the first group consist of  10 rats considered as a control group, while the second group treated with 0.05 ml\body weight\day of dipyron injected for 30 days duration. The  toxic effect of dipyrone was obvious in the different tissue and haematotoxic effects  . The histological changes were obvious in the hepatic cell whichof liver were  characterized by atrophy ,irregular hepatic cells ,RBC cells in the blood sinusoid. However,the spleen tissue contains nodule (white pulpe ).The bony tissue have osteocytes large bony vacuoles and the blood vessel were congested.
Keywords
Metamizole; Dipyrone; Rats
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