CYTOTOXICITY OF REGULAR AND FAST SET BIOCRAMIC MATERIALS | ||
| Egyptian Dental Journal | ||
| Article 55, Volume 65, Issue 3 - July (Fixed Prosthodontics, Dental Materials, Conservative Dentistry & Endodontics), July 2019, Pages 2993-2997 PDF (249.06 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/edj.2019.72694 | ||
| Author | ||
| Loai Alsofi | ||
| Assistant Professor, Department of Endodontics, Faculty of Dentistry, King Abdulaziz University | ||
| Abstract | ||
| Aim: To compare the cytotoxic effect of regular and fast set Root Repair Materials using oral epithelial cells (OEC). Materials and methods: The cytotoxicity of the two forms was tested against OEC cells using Sulfo-rhodamine B (SRB) assay. The cells were exposed to the test compound for 72 hrs. Results: Both fast and regular set root repair materials showed a considerable cytotoxicity against OEC cells with IC50 of 3.0 and 3.4 μg/ml, respectively. Despite their moderate cytotoxic effect, the resistant fraction was relatively high for Fast and regular root repair composites (R-values equal 35.6% and 32.2%, respectively). Conclusions: Both fast and regular set of EndoSequence Root Repair Materials have a considerable cytotoxicity against OEC cells. Despite their moderate cytotoxic effect against the cells the resistant fraction was relatively high for both. | ||
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