Assessment of Biological markers level in gingival crevicular fluids during early orthodontic treatment of periodontally affected teeth | ||
| Egyptian Dental Journal | ||
| Article 3, Volume 64, Issue 1 - January (Orthodontics, Pediatric & Preventive Dentistry), January 2018, Pages 23-31 PDF (413.17 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/edj.2018.76361 | ||
| Authors | ||
| Fatma AbdelAziz1; Naglaa ElKilany2; Olfat Shaker3 | ||
| 1Assistant Professor at the Orthodontic Department, Faculty of Dental medicine for Girls, Al-Azhar University | ||
| 2Professor and Head of the Oral Radiology, Medicine, Periodontology and Diagnosis Department, Faculty of Dental Medicine for Girl’s, Al-Azhar University | ||
| 3Professor at Biochemistry Department, Faculty of Medicine, Cairo University | ||
| Abstract | ||
| Background: the aim of the present study was to evaluate the levels of some biological markers; interleukin 1B (IL1B), interleukin 6 (IL6), interleukin 8 (IL8) and prostaglandin(PG) in the gingival crevicular fluids (GCF) in patients with periodontal disease during early stage of orthodontic tooth movement. Subjects and methods: The study included 9 subjects with age range 23-45 years, with periodontally affected teeth submitted to orthodontic treatment at the orthodontic department faculty of dentistry, Al-azhar University,Girls branch. Fixed appliances were inserted, nickel titanium light archwires were used for levelling and alignment. Gingival crevicular fluid (GCF) samples were collected from the healthy and periodontally affected teeth with paper points at base line, 3 days, 1,2,3,4 weeks from starting of orthodontic treatment. Results: during the test period, the levels of IL 6 in healthy teeth and periodontally affected teeth gradually increased after 3 days and 1 week, then gradually decreased after 2 and 3 weeks, Comparing healthy and periodontally affected teeth revealed a higher levels in periodontally affected teeth.. The mean value of IL 8 gradually increased after 3 days and 1 week, then gradually decreased after 2 and 3 weeks. the mean value of IL 1B was gradually increased after 3 days and 1 week, then gradually decreased after 2 and 3 week. PG showed gradual increase after 3 days and 1 week, then gradually decreased after 2, 3 and 4weeks. Comparing healthy and periodontally affected teeth revealed a higher levels in periodontally affected teeth. Conclusion: Our findings suggested that the orthodontic movement of periodontally compromised teeth result in significant changes in the levels of certain biological markers in the GCF as compared to healthy teeth. | ||
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