Molecular, Histological and Biochemical Effects of Tea Seed Cake on Hepatic and Renal Functions of Oreochromis niloticus | ||
| Journal of Applied Plant Protection | ||
| Article 3, Volume 1, Issue 1, December 2013, Pages 27-32 PDF (622.7 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/japp.2013.7721 | ||
| Authors | ||
| Mosleh I.1; M. Afifi2 | ||
| 1Department of Aquatic Environment, Faculty of Fish Resources, Suez University, Egypt &Department of Biological Sciences, Faculty of Science, King Abdulaziz University, North Campus, PO Box 11508, Jeddah, 21463, Saudi Arabia. | ||
| 2Department of Biochemistry, Faculty of Veterinary Medicine, Zagazig University, Egypt | ||
| Abstract | ||
| Tea seed cake is a plant derivative with pesticide properties mainly used for eradication of unwanted fish, it easily degraded in water leaving an organic fertilizer so it is safe for the environment, this work aimed to study it's toxic effect on the widely farmed fish in Egypt; Oreochromis niloticus throughout this study its molecular, histological and biochemical effects on liver and kidney of O. niloticus fingerlings exposed to different concentration of tea seed cake (1/3, 1/10 and 1/20 LC50). There were an increase of hepatic and renal biomarkers, alanin aminotransferas (ALT), creatinin and urea concentrations in serum this concomitant with different pathological changes in hepatic and kidney tissue mainly vacuolization, degeneration, nicrosis, lymphocytic infiltration and haemolysis as well an induction of superoxid dismutas (SOD) and catalase (CAT) gene expression and increase of their activities in renal and hepatic tissues of the exposed fish. | ||
| Keywords | ||
| Tea seed cake; biomarkers; SOD and CAT gene expression | ||
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