Radwan, I., Radi, A. (2010). Antimicrobial activity of some cephalosporins with special reference to their effects on body weight and immune response to Newcastle disease vaccine in fayoumy chicks. test, 20(1), 236-242. doi: 10.21608/jvmr.2020.77607
I. A. Radwan; Abeer M. Radi. "Antimicrobial activity of some cephalosporins with special reference to their effects on body weight and immune response to Newcastle disease vaccine in fayoumy chicks". test, 20, 1, 2010, 236-242. doi: 10.21608/jvmr.2020.77607
Radwan, I., Radi, A. (2010). 'Antimicrobial activity of some cephalosporins with special reference to their effects on body weight and immune response to Newcastle disease vaccine in fayoumy chicks', test, 20(1), pp. 236-242. doi: 10.21608/jvmr.2020.77607
Radwan, I., Radi, A. Antimicrobial activity of some cephalosporins with special reference to their effects on body weight and immune response to Newcastle disease vaccine in fayoumy chicks. test, 2010; 20(1): 236-242. doi: 10.21608/jvmr.2020.77607

Antimicrobial activity of some cephalosporins with special reference to their effects on body weight and immune response to Newcastle disease vaccine in fayoumy chicks

Journal of Veterinary Medical Research
Article 34, Volume 20, Issue 1, March 2010, Pages 236-242    PDF (221.77 K)
Document Type: Original Article
DOI: 10.21608/jvmr.2020.77607
Authors
I. A. Radwan1; Abeer M. Radi2
1Microbiology Department, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt.
2Pharmacology Department, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt.
Abstract
The susceptibility of the most common bacterial pathogens, namely E. coli, P. mirabilis and Ps. aeroginosa which were isolated from egg incubators and yolk sacs of randomly selected one day old Fayoumy chicks to three selected cephalosporins (cephradine, ceftiofur and cefquinome) were studied. The minimum inhibitory concentration (MIC), the minimum bactericidal concentration (MBC) of the tested drugs and the effect of these antibiotics on the body weight gain, mortality and immune response against Newcastle disease (ND) vaccine of the same bread of chicks were also estimated. The tested organisms were sensitive to ceftiofur and cefquinome whereas E.coli and ps. aeroginosa were found to be resistant to cephradine. The results showed that mortalities were higher in control and cephradine treated groups, while it was lower in the ceftiofur and cefquinome treated groups. On the other hand, the lowest mean body weight was recorded in control group (155.7±6.55 gm) followed by ceftiofur treated group (162.5±2.06 gm) and the highest mean body weight was recorded in cefquinome treated group (183.5±1.66 gm, p < 0.01) at 30 days of age. The study revealed that the tested antibiotics not exert any immune suppressive effect against (ND) vaccine.
Keywords
Antimicrobial; activity; cephalosporins; special; reference; Effects; body; weight; Immune; Response; Newcastle; Disease; vaccine; fayoumy; chicks
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