M. Ibrahim, H., M. Souror, Z., Sherif, N., Lotfy, M., A. El Ebiary, E., Makharita, M. (2010). Efficacy of living attenuated Salmonella typhimurium vaccine in poultry. test, 20(1), 260-262. doi: 10.21608/jvmr.2020.77611
Hanan M. Ibrahim; Zeinab M. Souror; N.A. Sherif; M. M. Lotfy; Elham A. El Ebiary; M. A. Makharita. "Efficacy of living attenuated Salmonella typhimurium vaccine in poultry". test, 20, 1, 2010, 260-262. doi: 10.21608/jvmr.2020.77611
M. Ibrahim, H., M. Souror, Z., Sherif, N., Lotfy, M., A. El Ebiary, E., Makharita, M. (2010). 'Efficacy of living attenuated Salmonella typhimurium vaccine in poultry', test, 20(1), pp. 260-262. doi: 10.21608/jvmr.2020.77611
M. Ibrahim, H., M. Souror, Z., Sherif, N., Lotfy, M., A. El Ebiary, E., Makharita, M. Efficacy of living attenuated Salmonella typhimurium vaccine in poultry. test, 2010; 20(1): 260-262. doi: 10.21608/jvmr.2020.77611

Efficacy of living attenuated Salmonella typhimurium vaccine in poultry

Journal of Veterinary Medical Research
Article 38, Volume 20, Issue 1, March 2010, Pages 260-262    PDF (150.19 K)
Document Type: Original Article
DOI: 10.21608/jvmr.2020.77611
Authors
Hanan M. Ibrahim1; Zeinab M. Souror1; N.A. Sherif1; M. M. Lotfy1; Elham A. El Ebiary2; M. A. Makharita1
1Central Laboratory for Evaluation of Veterinary Biologics, Abbasia, Cairo, Egypt.
2Central Laboratory for Evaluation of Veterinary Biologics, Abbasia, Cairo, Egypt
Abstract
The main goal of this study was to evaluate the protective efficacy of living attenuated Salmonella Typhimurium (S. Typhimurium) vaccine in poultry and to evaluate its use in control of salmonella infection in chickens. Oral vaccination of chickens within 36 hours after hatching and after 6 weeks from the first dose induced a strong humoral immune response as measured by ELISA. Challenge test was done with virulent strain of S. Typhimurium. Shedding of S. Typhimurium was detected during the first day, but after 14 days, salmonella could not be detected in the internal organs of vaccinated chickens compared with the non-vaccinated challenged chickens.
Keywords
Efficacy; living; attenuated; Salmonella; typhimurium; vaccine; Poultry
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