Effect of Moringa Leaves and Seeds on Osteoporosis in Rats | ||
| Journal of Food and Dairy Sciences | ||
| Article 17, Volume 03, Issue 3, 2018, Pages 129-135 PDF (370.49 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jfds.2018.77771 | ||
| Authors | ||
| M. K. Habib1; Maalem H. Al-Moalem2 | ||
| 1Nutrition and Food Science Department, Faculty of Home Economics, Helwan University, Cairo, Egypt., | ||
| 2Prince Sattam Bin Abdulaziz University, College of Education-Delam, Department of Home Economics, Kingdom Saudi Arabia. | ||
| Abstract | ||
| Osteoporosis (OP) speaks to most regular metabolic bone maladies. This study was conducted to study the impact of Moringa oleifera leaves and seeds and their blends on osteoporosis in rats. Thirty five adult female albino of rats, of (180 ± 10 g) were divided into five groups, the first group, negative control group (-ve) and fed on basal diet only, the other four groups (7 rats each) were fed on basal diet containing 100 mg Prednisone Acetate as source of glucocorticoid/ kg diet to induce osteoporosis for two weeks. One group of them was served as a positive control group, the other three groups were fed on prednisone acetate diets containing dried moringa leaves (2.5%), moringa seeds (2.5%) and 2.5% of their combination at (1:1), respectively. Blood samples and femur bones were collected for estimating both serum and bone markers of osteoporosis. The results indicated that, supplementation with Moringa oleifera leaves and seeds and their combinations significantly increased (P<0.05) serum Ca and P in osteoporotic rats. There was significant increase (P<0.05) in serum free thyroxin (T4) and a significant decrease (P<0.05) in parathormone (PTH) in osteoporotic rats. Femur bone mineral density (BMD) were also significantly increased. The present examination suggested utilizing Moringa oleifera leaves and seeds and their blends as a good anti-osteoporotic activity. | ||
| Keywords | ||
| Osteoporosis; Moringa oleifera; leaves; seeds; Flavonoids; Rats | ||
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